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- W1980531133 abstract "Patients with schizophrenia manifest a high degree of generalized neurocognitive dysfunction, with particularly severe impairment in memory. There is growing interest in patient awareness of clinical and cognitive symptoms, since this has implications for treatment compliance and outcome. The present study reports preliminary data addressing awareness of memory dysfunction and its impact on daily activities in a cohort of prospectively ascertained first-episode patients with schizophrenia. Fourteen patients meeting DSM-IV criteria for schizophrenia or schizoaffective disorder rated their daily memory function in a number of real-life contexts and received formal neurocognitive tests of memory. Family members independently rated patient memory function, using the same item content that were performed in patient self-ratings. The results revealed a surprising concordance between patient and observer ratings of daily memory function; absolute scores of patients ratings did not differ significantly from observer ratings, though the correlation between patients and observers was less consistent. Both patients and informants agreed on ratings of the quality of recent episodic memory. Patient ratings of daily memory function correlated modestly with test based assessment of memory (range of correlations: .33 to 45). Informant ratings of recent episodic memory were more consistently associated with actual patient performance, particularly on measures of working memory and explicit recall. The findings indicate that patients have partial awareness of memory function as it impacts on recall of daily episodes. Test based assessment of memory provides an indirect indication of global memory capability in real-world situations, but is less directly associated with more specific daily functions." @default.
- W1980531133 created "2016-06-24" @default.
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- W1980531133 date "2000-04-01" @default.
- W1980531133 modified "2023-09-28" @default.
- W1980531133 title "96. Awareness of memory dysfunction in first-episode schizophrenia" @default.
- W1980531133 doi "https://doi.org/10.1016/s0006-3223(00)00358-9" @default.
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