FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980532029> ?p ?o ?g. }

• W1980532029 endingPage "931" @default.
• W1980532029 startingPage "921" @default.
• W1980532029 abstract "Since its discovery nearly 20 years ago, the Ron receptor tyrosine kinase has been extensively studied. These studies have elucidated many of the major signaling pathways activated by Ron. In the context of the inflammation and cancer, studies have shown that Ron plays differential roles; Ron activation limits the inflammatory response, whereas in cancer, Ron activation is associated with increased metastases and poor prognosis.This review discusses the current literature with regard to Ron signaling and consequences of its activation in cancer as well as its role in cancer therapy. Further, we discuss the mechanisms by which Ron influences the inflammatory response and its role in chronic inflammatory diseases. Finally, we discuss Ron's connection between chronic inflammation and progression to cancer.The complex nature of Ron's signaling paradigm necessitates additional studies to understand the pathways by which Ron is functioning and how these differ in inflammation and cancer. This will be vital to understanding the impact that Ron signaling has in disease states. Additional studies of targeted therapies, either alone or in conjunction with current therapies are needed to determine if inhibition of Ron signaling will provide long-term benefits to cancer patients." @default.
• W1980532029 created "2016-06-24" @default.
• W1980532029 creator A5031387848 @default.
• W1980532029 creator A5040302140 @default.
• W1980532029 date "2012-07-26" @default.
• W1980532029 modified "2023-09-26" @default.
• W1980532029 title "Ron receptor tyrosine kinase signaling as a therapeutic target" @default.
• W1980532029 cites W106620489 @default.
• W1980532029 cites W1485133278 @default.
• W1980532029 cites W1491063649 @default.
• W1980532029 cites W1495297644 @default.
• W1980532029 cites W1502579708 @default.
• W1980532029 cites W1542053886 @default.
• W1980532029 cites W1585747919 @default.
• W1980532029 cites W1607589687 @default.
• W1980532029 cites W1639729138 @default.
• W1980532029 cites W1859164552 @default.
• W1980532029 cites W1867533050 @default.
• W1980532029 cites W1907787906 @default.
• W1980532029 cites W1963853720 @default.
• W1980532029 cites W1965825929 @default.
• W1980532029 cites W1966828606 @default.
• W1980532029 cites W1969446537 @default.
• W1980532029 cites W1972267806 @default.
• W1980532029 cites W1974574003 @default.
• W1980532029 cites W1974783503 @default.
• W1980532029 cites W1975073587 @default.
• W1980532029 cites W1975401288 @default.
• W1980532029 cites W1975837291 @default.
• W1980532029 cites W1990050705 @default.
• W1980532029 cites W1992436751 @default.
• W1980532029 cites W1994029123 @default.
• W1980532029 cites W1999508213 @default.
• W1980532029 cites W2000925949 @default.
• W1980532029 cites W2004860441 @default.
• W1980532029 cites W2005903270 @default.
• W1980532029 cites W2007622641 @default.
• W1980532029 cites W2010852376 @default.
• W1980532029 cites W2012808819 @default.
• W1980532029 cites W2013878853 @default.
• W1980532029 cites W2020098501 @default.
• W1980532029 cites W2022161594 @default.
• W1980532029 cites W2024280581 @default.
• W1980532029 cites W2024721474 @default.
• W1980532029 cites W2026484424 @default.
• W1980532029 cites W2030061983 @default.
• W1980532029 cites W2034682226 @default.
• W1980532029 cites W2036604677 @default.
• W1980532029 cites W2037980364 @default.
• W1980532029 cites W2038409424 @default.
• W1980532029 cites W2038902703 @default.
• W1980532029 cites W2045573810 @default.
• W1980532029 cites W2047903289 @default.
• W1980532029 cites W2048610507 @default.
• W1980532029 cites W2053666128 @default.
• W1980532029 cites W2055247813 @default.
• W1980532029 cites W2056295525 @default.
• W1980532029 cites W2065243282 @default.
• W1980532029 cites W2066646758 @default.
• W1980532029 cites W2077120503 @default.
• W1980532029 cites W2078658029 @default.
• W1980532029 cites W2086594085 @default.
• W1980532029 cites W2089766601 @default.
• W1980532029 cites W2090247319 @default.
• W1980532029 cites W2091362876 @default.
• W1980532029 cites W2092942075 @default.
• W1980532029 cites W2097257853 @default.
• W1980532029 cites W2097644281 @default.
• W1980532029 cites W2104669784 @default.
• W1980532029 cites W2105635784 @default.
• W1980532029 cites W2111005353 @default.
• W1980532029 cites W2112331487 @default.
• W1980532029 cites W2113856817 @default.
• W1980532029 cites W2118874445 @default.
• W1980532029 cites W2118942065 @default.
• W1980532029 cites W2119575586 @default.
• W1980532029 cites W2129875426 @default.
• W1980532029 cites W2130522236 @default.
• W1980532029 cites W2130921495 @default.
• W1980532029 cites W2142419137 @default.
• W1980532029 cites W2142738109 @default.
• W1980532029 cites W2145372211 @default.
• W1980532029 cites W2147857032 @default.
• W1980532029 cites W2148901520 @default.
• W1980532029 cites W2155775657 @default.
• W1980532029 cites W2166629969 @default.
• W1980532029 cites W2172255447 @default.
• W1980532029 cites W2244368680 @default.
• W1980532029 cites W2312309812 @default.
• W1980532029 cites W2330451300 @default.
• W1980532029 cites W2411267578 @default.
• W1980532029 doi "https://doi.org/10.1517/14728222.2012.710200" @default.
• W1980532029 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4075176" @default.
• W1980532029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22834780" @default.
• W1980532029 hasPublicationYear "2012" @default.
• W1980532029 type Work @default.
• W1980532029 sameAs 1980532029 @default.
• W1980532029 citedByCount "31" @default.

• next