FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980572143> ?p ?o ?g. }

• W1980572143 abstract "We evaluated whether best overall response changes by designating primary renal lesions as either target or nontarget lesions and assessing response per Response Evaluation Criteria in Solid Tumors in mRCC patients treated with sunitinib. In addition, we evaluated whether discordance, if any, leads to a difference in predictive value of response in terms of time to progression (TTP) and overall survival (OS).Patients with mRCC with an intact primary tumor and at least 1 extrarenal measurable lesion were included in this study. The variation of the sum of diameters (ΔSOD) of target lesions and best overall response, assessed from all target lesions and from metastasis-only target lesions, was documented separately.There were 41 patients included. Median ΔSOD of the primary lesion and metastatic target lesion were -6.0% (range, -34.0% to 17.6%), and -18.0% (range, -100.0% to 120.0%), respectively. For metastasis-only target lesions, the best overall response of 2 patients (4.9%) changed from stable disease to partial response. When we categorized patients into responders and nonresponders, response determination using metastasis-only target lesions resulted in significantly better discrimination of time to progression (14.9 vs. 4.3 months, P = .001) and overall survival (18.5 vs. 9.6 months, P = .036) between 2 groups. Using all target lesions, both TTP (14.9 vs. 5.4 months, P = .056) and OS (18.0 vs. 10.6 months, P = .155) were not statistically significant.When treating nonnephrectomized mRCC patients, selecting metastasis-only lesions as target lesions might be better to determine response, which might be more representative of survival end point." @default.
• W1980572143 created "2016-06-24" @default.
• W1980572143 creator A5007931207 @default.
• W1980572143 creator A5007992707 @default.
• W1980572143 creator A5025736986 @default.
• W1980572143 creator A5025787561 @default.
• W1980572143 creator A5045648382 @default.
• W1980572143 creator A5047657377 @default.
• W1980572143 creator A5052223687 @default.
• W1980572143 creator A5063838757 @default.
• W1980572143 creator A5066756823 @default.
• W1980572143 creator A5072419569 @default.
• W1980572143 creator A5079154981 @default.
• W1980572143 creator A5079540101 @default.
• W1980572143 date "2013-09-01" @default.
• W1980572143 modified "2023-10-10" @default.
• W1980572143 title "Response Evaluation Criteria in Solid Tumors Response of the Primary Lesion in Metastatic Renal Cell Carcinomas Treated With Sunitinib: Does the Primary Lesion Have to Be Regarded as a Target Lesion?" @default.
• W1980572143 cites W1977860578 @default.
• W1980572143 cites W1979752037 @default.
• W1980572143 cites W1993117548 @default.
• W1980572143 cites W1993849812 @default.
• W1980572143 cites W1995098380 @default.
• W1980572143 cites W1996314285 @default.
• W1980572143 cites W1998005755 @default.
• W1980572143 cites W2019607817 @default.
• W1980572143 cites W2021256410 @default.
• W1980572143 cites W2032157317 @default.
• W1980572143 cites W2039698853 @default.
• W1980572143 cites W2040259869 @default.
• W1980572143 cites W2099752220 @default.
• W1980572143 cites W2105677187 @default.
• W1980572143 cites W2106347399 @default.
• W1980572143 cites W2109996356 @default.
• W1980572143 cites W2116661424 @default.
• W1980572143 cites W2135916881 @default.
• W1980572143 cites W2141849536 @default.
• W1980572143 cites W2145473922 @default.
• W1980572143 cites W2149456801 @default.
• W1980572143 cites W2162439819 @default.
• W1980572143 doi "https://doi.org/10.1016/j.clgc.2012.12.005" @default.
• W1980572143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23332873" @default.
• W1980572143 hasPublicationYear "2013" @default.
• W1980572143 type Work @default.
• W1980572143 sameAs 1980572143 @default.
• W1980572143 citedByCount "2" @default.
• W1980572143 countsByYear W19805721432017 @default.
• W1980572143 crossrefType "journal-article" @default.
• W1980572143 hasAuthorship W1980572143A5007931207 @default.
• W1980572143 hasAuthorship W1980572143A5007992707 @default.
• W1980572143 hasAuthorship W1980572143A5025736986 @default.
• W1980572143 hasAuthorship W1980572143A5025787561 @default.
• W1980572143 hasAuthorship W1980572143A5045648382 @default.
• W1980572143 hasAuthorship W1980572143A5047657377 @default.
• W1980572143 hasAuthorship W1980572143A5052223687 @default.
• W1980572143 hasAuthorship W1980572143A5063838757 @default.
• W1980572143 hasAuthorship W1980572143A5066756823 @default.
• W1980572143 hasAuthorship W1980572143A5072419569 @default.
• W1980572143 hasAuthorship W1980572143A5079154981 @default.
• W1980572143 hasAuthorship W1980572143A5079540101 @default.
• W1980572143 hasConcept C121608353 @default.
• W1980572143 hasConcept C126322002 @default.
• W1980572143 hasConcept C142724271 @default.
• W1980572143 hasConcept C143998085 @default.
• W1980572143 hasConcept C2776694085 @default.
• W1980572143 hasConcept C2777472916 @default.
• W1980572143 hasConcept C2778822529 @default.
• W1980572143 hasConcept C2779013556 @default.
• W1980572143 hasConcept C2779490328 @default.
• W1980572143 hasConcept C2779984678 @default.
• W1980572143 hasConcept C2780283643 @default.
• W1980572143 hasConcept C2780400711 @default.
• W1980572143 hasConcept C2781156865 @default.
• W1980572143 hasConcept C2781464078 @default.
• W1980572143 hasConcept C500558357 @default.
• W1980572143 hasConcept C71924100 @default.
• W1980572143 hasConceptScore W1980572143C121608353 @default.
• W1980572143 hasConceptScore W1980572143C126322002 @default.
• W1980572143 hasConceptScore W1980572143C142724271 @default.
• W1980572143 hasConceptScore W1980572143C143998085 @default.
• W1980572143 hasConceptScore W1980572143C2776694085 @default.
• W1980572143 hasConceptScore W1980572143C2777472916 @default.
• W1980572143 hasConceptScore W1980572143C2778822529 @default.
• W1980572143 hasConceptScore W1980572143C2779013556 @default.
• W1980572143 hasConceptScore W1980572143C2779490328 @default.
• W1980572143 hasConceptScore W1980572143C2779984678 @default.
• W1980572143 hasConceptScore W1980572143C2780283643 @default.
• W1980572143 hasConceptScore W1980572143C2780400711 @default.
• W1980572143 hasConceptScore W1980572143C2781156865 @default.
• W1980572143 hasConceptScore W1980572143C2781464078 @default.
• W1980572143 hasConceptScore W1980572143C500558357 @default.
• W1980572143 hasConceptScore W1980572143C71924100 @default.
• W1980572143 hasLocation W19805721431 @default.
• W1980572143 hasLocation W19805721432 @default.
• W1980572143 hasOpenAccess W1980572143 @default.
• W1980572143 hasPrimaryLocation W19805721431 @default.
• W1980572143 hasRelatedWork W1980572143 @default.
• W1980572143 hasRelatedWork W1994606873 @default.
• W1980572143 hasRelatedWork W2008374848 @default.
• W1980572143 hasRelatedWork W2096517981 @default.
• W1980572143 hasRelatedWork W2154171266 @default.

• next