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• W1980576528 abstract "Theoretical models have long pointed to the dentate gyrus as a possible source of neuronal pattern separation. In agreement with predictions from these models, we show that minimal changes in the shape of the environment in which rats are exploring can substantially alter correlated activity patterns among place-modulated granule cells in the dentate gyrus. When the environments are made more different, new cell populations are recruited in CA3 but not in the dentate gyrus. These results imply a dual mechanism for pattern separation in which signals from the entorhinal cortex can be decorrelated both by changes in coincidence patterns in the dentate gyrus and by recruitment of nonoverlapping cell assemblies in CA3." @default.
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• W1980576528 date "2007-02-16" @default.
• W1980576528 modified "2023-10-18" @default.
• W1980576528 title "Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus" @default.
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• W1980576528 doi "https://doi.org/10.1126/science.1135801" @default.
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