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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980590617> ?p ?o ?g. }

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• W1980590617 abstract "We have shown that an antibody (9C10) to the alpha 4 integrin induces apoptosis in murine immature CD4+ CD8+ thymocytes and in activated (but not resting) mature lymph node T cells. In both cases, apoptosis is blocked by the highly selective protein kinase C (PKC) inhibitor Ro31.8425, suggesting that 9C10 induces signalling through the alpha 4 integrin resulting in PKC activation leading to apoptosis. Overall, our results indicate the potential role of the alpha 4 integrin-mediated interactions in apoptosis induction during T-cell development and following mature T-cell activation." @default.
• W1980590617 created "2016-06-24" @default.
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• W1980590617 date "1997-11-01" @default.
• W1980590617 modified "2023-10-18" @default.
• W1980590617 title "Anti‐α4 integrin antibody induces apoptosis in murine thymocytes and staphylococcal enterotoxin B‐activated lymph node T cells" @default.
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• W1980590617 doi "https://doi.org/10.1046/j.1365-2567.1997.00351.x" @default.
• W1980590617 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1363791" @default.
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