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- W1980605573 abstract "Abstract Disturbances in lipid metabolism such as hypercholesterolemia or hypertriglyceridemia are widely accepted risk factor for atherosclerosis (1). Recent studies have suggested that a hypercoagulable state and a reduced fibrinolytic activity may also be independent risk factors for atherosclerotic vascular disease and thrombo-embolic complications (2–3). Moreover these studies should be considered with the significant evidence that shows several complex interactions which occur between the lipid and hemostatic system. In fact a positive correlation was found between Factor VII coagulant activity and dietary fat intake and between platelet thromboxane production and serum total cholesterol levels (4–6). Finally, several authors suggest a positive correlation between impaired fibrinolysis and serum triglyceride levels, whereas studies on fibrinolytic system in hypercholesterolemic patients are very few (7–9). The aim of this study was to verify the existence of a thrombophilic state in patients with type IIa hyperlipoproteinemia without signs of atherosclerotic vascular disease in order to suggest an appropriate primary prevention." @default.
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- W1980605573 date "1996-01-01" @default.
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- W1980605573 title "Activation of coagulation but normal fibrinolysis in patients with type IIa hyperlipoproteinemia" @default.
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- W1980605573 doi "https://doi.org/10.1016/0049-3848(95)00245-6" @default.
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