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- W198067878 abstract "Since the introduction of adjuvant chemotherapy to the armamentarium of anticancer weapons, the question as to the optimum duration of treatment had arisen. As no marker is available for the persistence of a minimal residual tumor cell population, the chemotherapist repeatedly faces the risk of overtreating patients who are cured, or of stopping the treatment of patients who are at risk of relapse. The discovery of a sensitive and specific tumor marker should hopefully help to resolve this kind of dilemma and to improve the efficacy of the treatment. It seems paradoxical, then, that neuroblastoma, which was one of the very first cancers to be biochemically traceable, is also the malignant tumor of childhood whose prognosis has been improved only negligibly by adjuvant chemotherapy. We briefly review here some of the studies on neuroblastoma markers and the problems related to their use in everyday oncologic practice." @default.
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- W198067878 date "1979-01-01" @default.
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- W198067878 title "Biologic Markers in Neuroblastoma" @default.
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- W198067878 doi "https://doi.org/10.1007/978-3-642-81320-7_11" @default.
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