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- W1980679031 abstract "Telomere dysfunction and fusion play key roles in driving genomic instability and clonal evolution in many tumor types. We have recently described a role for DNA ligase III (LIG3) in facilitating the escape of cells from crisis induced by telomere dysfunction. Our data indicate that LIG3-mediated telomere fusion is important in facilitating clonal evolution." @default.
- W1980679031 created "2016-06-24" @default.
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- W1980679031 date "2015-01-02" @default.
- W1980679031 modified "2023-09-24" @default.
- W1980679031 title "Alternative end joining, clonal evolution, and escape from a telomere-driven crisis" @default.
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- W1980679031 doi "https://doi.org/10.4161/23723556.2014.975623" @default.
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