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- W1980730968 abstract "<h3>BACKGROUND AND PURPOSE:</h3> Diagnostic test accuracy studies for ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy have shown inconclusive results due to their heterogenous study designs. Our aim was to compare the diagnostic accuracy of ultrasonography-guided fine-needle aspiration versus ultrasonography-guided core needle biopsy for detecting malignant tumors of the salivary gland and for the tissue-specific diagnosis of salivary gland tumors in a single tertiary hospital. <h3>MATERIALS AND METHODS:</h3> This retrospective study was approved by our institutional review board and informed consent was waived. Four hundred twelve patients who underwent ultrasonography-guided fine-needle aspiration (<i>n</i> = 155) or ultrasonography-guided core needle biopsy (<i>n</i> = 257) with subsequent surgical confirmation or clinical follow-up were enrolled. We compared the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy regarding malignant salivary gland tumors and the correct tissue-specific diagnosis of benign and malignant tumors. We also tested the difference between these procedures according to the operator9s experience and lesion characteristics. <h3>RESULTS:</h3> The inconclusive rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 19% and 4%, respectively (<i>P</i> < .001). The overall accuracy of ultrasonography-guided core needle biopsy for diagnosing malignant tumors was significantly higher than that of ultrasonography-guided fine-needle aspiration (<i>P</i> = .024). The correct tissue-specific diagnosis rates of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy were 95% versus 97% for benign tumors (<i>P</i> = .648) and 67% versus 80% for malignant tumors (<i>P</i> = .310). Trainees showed significantly lower accuracy with ultrasonography-guided fine-needle aspiration than with ultrasonography-guided core needle biopsy for diagnosing malignant tumors (<i>P</i> = .021). There was no difference between the diagnostic accuracy of ultrasonography-guided fine-needle aspiration and ultrasonography-guided core needle biopsy according to the internal composition of the lesions. There were no complications requiring intervention or hospitalization in our patients. <h3>CONCLUSIONS:</h3> Ultrasonography-guided core needle biopsy is superior to ultrasonography-guided fine-needle aspiration in detecting and characterizing malignant tumors of the salivary gland and could emerge as the diagnostic method of choice for patients presenting with a salivary gland mass." @default.
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- W1980730968 date "2015-02-12" @default.
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- W1980730968 title "Comparison of Fine-Needle Aspiration and Core Needle Biopsy under Ultrasonographic Guidance for Detecting Malignancy and for the Tissue-Specific Diagnosis of Salivary Gland Tumors" @default.
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- W1980730968 doi "https://doi.org/10.3174/ajnr.a4247" @default.
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