FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980732008> ?p ?o ?g. }

• W1980732008 endingPage "272" @default.
• W1980732008 startingPage "261" @default.
• W1980732008 abstract "Flush perfusion of the pulmonary artery with organ protection solution is a standard procedure before lung explantation. However, rapid flush perfusion may cause pulmonary oedema which is deleterious in the lung transplantation setting. In this study we tested the hypotheses that high pulmonary perfusion pressure contributes to the development of pulmonary oedema and positive end-expiratory pressure (PEEP) counteracts oedema formation. We expected oedema formation to increase weight and decrease compliance of the lungs on the basis of a decrease in alveolar volume as fluid replaces alveolar air spaces. The pulmonary artery of 28 isolated porcine lungs was perfused with a low-potassium dextrane solution at low (mean 27 mmHg) or high (mean 40 mmHg) pulmonary artery pressure (PAP) during mechanical ventilation at low (4 cmH(2)O) or high (8 cmH(2)O) PEEP, respectively. Following perfusion and storage, relative increases in lung weight were smaller (p < 0.05) during perfusion at low PAP (62 +/- 32% and 42 +/- 26%, respectively) compared to perfusion at high PAP (133 +/- 54% and 87 +/- 30%, respectively). Compared to all other PAP-PEEP combinations, increases in lung weight were smallest (44 +/- 9% and 27 +/- 12%, respectively), nonlinear intratidal lung compliance was largest (46% and 17% respectively, both p < 0.05) and lung histology showed least infiltration of mononuclear cells in the alveolar septa, and least alveolar destruction during the combination of low perfusion pressure and high PEEP. The findings suggest that oedema formation during pulmonary artery flush perfusion in isolated and ventilated lungs can be reduced by choosing low perfusion pressure and high PEEP. PAP-PEEP titration to minimize pulmonary oedema should be based on lung mechanics and PAP monitoring." @default.
• W1980732008 created "2016-06-24" @default.
• W1980732008 creator A5016638177 @default.
• W1980732008 creator A5023812725 @default.
• W1980732008 creator A5050663577 @default.
• W1980732008 creator A5070536813 @default.
• W1980732008 creator A5077057310 @default.
• W1980732008 creator A5078372569 @default.
• W1980732008 creator A5089136505 @default.
• W1980732008 date "2010-01-20" @default.
• W1980732008 modified "2023-09-27" @default.
• W1980732008 title "Low pulmonary artery flush perfusion pressure combined with high positive end-expiratory pressure reduces oedema formation in isolated porcine lungs" @default.
• W1980732008 cites W1600716279 @default.
• W1980732008 cites W1758009030 @default.
• W1980732008 cites W1818604216 @default.
• W1980732008 cites W1902593427 @default.
• W1980732008 cites W1974750100 @default.
• W1980732008 cites W1979143172 @default.
• W1980732008 cites W1989646123 @default.
• W1980732008 cites W1990153948 @default.
• W1980732008 cites W1997912073 @default.
• W1980732008 cites W2006701509 @default.
• W1980732008 cites W2007100753 @default.
• W1980732008 cites W2009478257 @default.
• W1980732008 cites W2011037002 @default.
• W1980732008 cites W2020205440 @default.
• W1980732008 cites W2024296291 @default.
• W1980732008 cites W2064991368 @default.
• W1980732008 cites W2072950206 @default.
• W1980732008 cites W2079144094 @default.
• W1980732008 cites W2079934375 @default.
• W1980732008 cites W2081725062 @default.
• W1980732008 cites W2090840588 @default.
• W1980732008 cites W2091512005 @default.
• W1980732008 cites W2095853601 @default.
• W1980732008 cites W2114084948 @default.
• W1980732008 cites W2116148466 @default.
• W1980732008 cites W2120276886 @default.
• W1980732008 cites W2142511555 @default.
• W1980732008 cites W2312655499 @default.
• W1980732008 cites W2336534281 @default.
• W1980732008 cites W2418323217 @default.
• W1980732008 cites W2597070792 @default.
• W1980732008 doi "https://doi.org/10.1088/0967-3334/31/2/011" @default.
• W1980732008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20086272" @default.
• W1980732008 hasPublicationYear "2010" @default.
• W1980732008 type Work @default.
• W1980732008 sameAs 1980732008 @default.
• W1980732008 citedByCount "11" @default.
• W1980732008 countsByYear W19807320082012 @default.
• W1980732008 countsByYear W19807320082013 @default.
• W1980732008 countsByYear W19807320082015 @default.
• W1980732008 countsByYear W19807320082016 @default.
• W1980732008 countsByYear W19807320082019 @default.
• W1980732008 crossrefType "journal-article" @default.
• W1980732008 hasAuthorship W1980732008A5016638177 @default.
• W1980732008 hasAuthorship W1980732008A5023812725 @default.
• W1980732008 hasAuthorship W1980732008A5050663577 @default.
• W1980732008 hasAuthorship W1980732008A5070536813 @default.
• W1980732008 hasAuthorship W1980732008A5077057310 @default.
• W1980732008 hasAuthorship W1980732008A5078372569 @default.
• W1980732008 hasAuthorship W1980732008A5089136505 @default.
• W1980732008 hasConcept C126322002 @default.
• W1980732008 hasConcept C136936797 @default.
• W1980732008 hasConcept C146957229 @default.
• W1980732008 hasConcept C164705383 @default.
• W1980732008 hasConcept C2777714996 @default.
• W1980732008 hasConcept C2778435157 @default.
• W1980732008 hasConcept C2778917391 @default.
• W1980732008 hasConcept C2780940725 @default.
• W1980732008 hasConcept C2781448352 @default.
• W1980732008 hasConcept C42219234 @default.
• W1980732008 hasConcept C71924100 @default.
• W1980732008 hasConceptScore W1980732008C126322002 @default.
• W1980732008 hasConceptScore W1980732008C136936797 @default.
• W1980732008 hasConceptScore W1980732008C146957229 @default.
• W1980732008 hasConceptScore W1980732008C164705383 @default.
• W1980732008 hasConceptScore W1980732008C2777714996 @default.
• W1980732008 hasConceptScore W1980732008C2778435157 @default.
• W1980732008 hasConceptScore W1980732008C2778917391 @default.
• W1980732008 hasConceptScore W1980732008C2780940725 @default.
• W1980732008 hasConceptScore W1980732008C2781448352 @default.
• W1980732008 hasConceptScore W1980732008C42219234 @default.
• W1980732008 hasConceptScore W1980732008C71924100 @default.
• W1980732008 hasIssue "2" @default.
• W1980732008 hasLocation W19807320081 @default.
• W1980732008 hasLocation W19807320082 @default.
• W1980732008 hasOpenAccess W1980732008 @default.
• W1980732008 hasPrimaryLocation W19807320081 @default.
• W1980732008 hasRelatedWork W1972386156 @default.
• W1980732008 hasRelatedWork W1980732008 @default.
• W1980732008 hasRelatedWork W2009244075 @default.
• W1980732008 hasRelatedWork W2061049773 @default.
• W1980732008 hasRelatedWork W2129154336 @default.
• W1980732008 hasRelatedWork W2171892859 @default.
• W1980732008 hasRelatedWork W2361027249 @default.
• W1980732008 hasRelatedWork W2409098256 @default.
• W1980732008 hasRelatedWork W3007372527 @default.

• next