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• W1980850755 endingPage "2441" @default.
• W1980850755 startingPage "2427" @default.
• W1980850755 abstract "Animal models of tinnitus allow us to study the relationship between changes in neural activity and the tinnitus percept. Here, guinea pigs were subjected to unilateral noise trauma and tested behaviourally for tinnitus 8 weeks later. By comparing animals with tinnitus with those without, all of which were noise-exposed, we were able to identify changes unique to the tinnitus group. Three physiological markers known to change following noise exposure were examined: spontaneous firing rates (SFRs) and burst firing in the inferior colliculus (IC), evoked auditory brainstem responses (ABRs), and the number of neurons in the cochlear nucleus containing nitric oxide synthase (NOS). We obtained behavioural evidence of tinnitus in 12 of 16 (75%) animals. Both SFRs and incidences of burst firing were elevated in the IC of all noise-exposed animals, but there were no differences between tinnitus and no-tinnitus animals. There were significant decreases in ipsilateral ABR latencies in tinnitus animals, contrary to what might be expected with a small hearing loss. Furthermore, there was an ipsilateral-contralateral asymmetry in NOS staining in the ventral cochlear nucleus (VCN) that was only apparent in tinnitus animals. Tinnitus animals had a significantly greater number of NOS-containing neurons on the noise-exposed side, whereas no-tinnitus animals did not. These data suggest that measuring NOS in the VCN and recording ABRs supplement behavioural methods for confirming tinnitus in animals, and that nitric oxide is involved in plastic neural changes associated with tinnitus." @default.
• W1980850755 created "2016-06-24" @default.
• W1980850755 creator A5008837092 @default.
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• W1980850755 creator A5088400104 @default.
• W1980850755 date "2014-04-05" @default.
• W1980850755 modified "2023-10-05" @default.
• W1980850755 title "Neural changes accompanying tinnitus following unilateral acoustic trauma in the guinea pig" @default.
• W1980850755 cites W1501988144 @default.
• W1980850755 cites W182286290 @default.
• W1980850755 cites W1914025541 @default.
• W1980850755 cites W1964221538 @default.
• W1980850755 cites W1966056190 @default.
• W1980850755 cites W1967087682 @default.
• W1980850755 cites W1969752840 @default.
• W1980850755 cites W1974528497 @default.
• W1980850755 cites W1976798000 @default.
• W1980850755 cites W1978441796 @default.
• W1980850755 cites W1978648371 @default.
• W1980850755 cites W1979404773 @default.
• W1980850755 cites W1979513610 @default.
• W1980850755 cites W1979609810 @default.
• W1980850755 cites W1982190764 @default.
• W1980850755 cites W1983502867 @default.
• W1980850755 cites W1985164074 @default.
• W1980850755 cites W1986103084 @default.
• W1980850755 cites W1988218008 @default.
• W1980850755 cites W1988756143 @default.
• W1980850755 cites W1994796196 @default.
• W1980850755 cites W1997798704 @default.
• W1980850755 cites W2001002884 @default.
• W1980850755 cites W2002001750 @default.
• W1980850755 cites W2002100764 @default.
• W1980850755 cites W2003052230 @default.
• W1980850755 cites W2004694849 @default.
• W1980850755 cites W2004758573 @default.
• W1980850755 cites W2006058593 @default.
• W1980850755 cites W2006604893 @default.
• W1980850755 cites W2008422389 @default.
• W1980850755 cites W2012284510 @default.
• W1980850755 cites W2012456328 @default.
• W1980850755 cites W2013611687 @default.
• W1980850755 cites W2014528664 @default.
• W1980850755 cites W2017526082 @default.
• W1980850755 cites W2018088637 @default.
• W1980850755 cites W2019674556 @default.
• W1980850755 cites W2021086875 @default.
• W1980850755 cites W2021848276 @default.
• W1980850755 cites W2024972257 @default.
• W1980850755 cites W2035464530 @default.
• W1980850755 cites W2035880314 @default.
• W1980850755 cites W2036858603 @default.
• W1980850755 cites W2038247692 @default.
• W1980850755 cites W2038262310 @default.
• W1980850755 cites W2038794139 @default.
• W1980850755 cites W2039999274 @default.
• W1980850755 cites W2042452336 @default.
• W1980850755 cites W2043239984 @default.
• W1980850755 cites W2048818224 @default.
• W1980850755 cites W2050066016 @default.
• W1980850755 cites W2054030359 @default.
• W1980850755 cites W2054379176 @default.
• W1980850755 cites W2055585046 @default.
• W1980850755 cites W2055620557 @default.
• W1980850755 cites W2056829537 @default.
• W1980850755 cites W2057567815 @default.
• W1980850755 cites W2057853918 @default.
• W1980850755 cites W2057902007 @default.
• W1980850755 cites W2057965149 @default.
• W1980850755 cites W2059588207 @default.
• W1980850755 cites W2064510386 @default.
• W1980850755 cites W2066577814 @default.
• W1980850755 cites W2066956489 @default.
• W1980850755 cites W2068334533 @default.
• W1980850755 cites W2068696003 @default.
• W1980850755 cites W2070197876 @default.
• W1980850755 cites W2071146246 @default.
• W1980850755 cites W2072194424 @default.
• W1980850755 cites W2074477628 @default.
• W1980850755 cites W2074953902 @default.
• W1980850755 cites W2075050776 @default.
• W1980850755 cites W2082048768 @default.
• W1980850755 cites W2082495008 @default.
• W1980850755 cites W2084059718 @default.
• W1980850755 cites W2086175702 @default.
• W1980850755 cites W2089796673 @default.
• W1980850755 cites W2089987432 @default.
• W1980850755 cites W2090545077 @default.
• W1980850755 cites W2092526100 @default.
• W1980850755 cites W2092694980 @default.
• W1980850755 cites W2097860097 @default.
• W1980850755 cites W2103112457 @default.
• W1980850755 cites W2118058488 @default.
• W1980850755 cites W2122865581 @default.
• W1980850755 cites W2124698022 @default.

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