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- W1980858359 abstract "Importance of the field: The mucosal delivery of vaccines provides the basis for induction of humoral, cellular and mucosal immune responses against infectious diseases. The delivery of antigens to and through mucosal barriers always remains challenging due to adverse physiological conditions (pH and enzymes) and biological barriers created by tight epithelial junctions restricting transportation of macromolecules. Mucoadhesive and biodegradable polymers offer numerous advantages in therapeutic delivery of proteins/antigens particularly through the mucosal route by protecting antigens from degradation, increasing concentration of antigen in the vicinity of mucosal tissue for better absorption, extending their residence time in the body and/or targeting them to sites of antigen uptake. Furthermore, antigen can be delivered more effectively to the antigen presenting cells by anchoring the ligand having affinity on the surface of carrier for the receptors present on the mucosal epithelial cells.Areas covered in this review: The present review covers various polymeric carriers, which allow the possibility of modification and manipulation of their properties, thereby, enhancing the effectiveness of mucosal vaccines. This article reviews the recent literature and patents in the field of vaccine delivery using mucoadhesive polymeric carriers.What the reader will gain: The reader will gain insights into various natural polymers, synthetic polymers and ligand derived polymeric carrier systems studied to enhance mucosal immunization.Take home message: Biodegradable polymeric carriers represent a promising approach for mucosal delivery of vaccine." @default.
- W1980858359 created "2016-06-24" @default.
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- W1980858359 date "2010-03-29" @default.
- W1980858359 modified "2023-09-26" @default.
- W1980858359 title "Recent advances in mucosal delivery of vaccines: role of mucoadhesive/biodegradable polymeric carriers" @default.
- W1980858359 cites W138487434 @default.
- W1980858359 cites W1498725963 @default.
- W1980858359 cites W1526823328 @default.
- W1980858359 cites W1535141082 @default.
- W1980858359 cites W1568216484 @default.
- W1980858359 cites W1845975704 @default.
- W1980858359 cites W1906564878 @default.
- W1980858359 cites W1907467614 @default.
- W1980858359 cites W1953576556 @default.
- W1980858359 cites W1972238739 @default.
- W1980858359 cites W1973230016 @default.
- W1980858359 cites W1974972571 @default.
- W1980858359 cites W1980175064 @default.
- W1980858359 cites W1981256948 @default.
- W1980858359 cites W1981406243 @default.
- W1980858359 cites W1982686464 @default.
- W1980858359 cites W1982938211 @default.
- W1980858359 cites W1990236675 @default.
- W1980858359 cites W1994327932 @default.
- W1980858359 cites W1994852714 @default.
- W1980858359 cites W2000319611 @default.
- W1980858359 cites W2003614362 @default.
- W1980858359 cites W2005246945 @default.
- W1980858359 cites W2005310862 @default.
- W1980858359 cites W2009857985 @default.
- W1980858359 cites W2012610027 @default.
- W1980858359 cites W2013002996 @default.
- W1980858359 cites W2013103459 @default.
- W1980858359 cites W2013833904 @default.
- W1980858359 cites W2016471012 @default.
- W1980858359 cites W2018689770 @default.
- W1980858359 cites W2019836676 @default.
- W1980858359 cites W2022633264 @default.
- W1980858359 cites W2028294518 @default.
- W1980858359 cites W2029173451 @default.
- W1980858359 cites W2030296249 @default.
- W1980858359 cites W2034783507 @default.
- W1980858359 cites W2039046378 @default.
- W1980858359 cites W2040079748 @default.
- W1980858359 cites W2040771740 @default.
- W1980858359 cites W2042977409 @default.
- W1980858359 cites W2043669485 @default.
- W1980858359 cites W2043886290 @default.
- W1980858359 cites W2051977226 @default.
- W1980858359 cites W2053467893 @default.
- W1980858359 cites W2053944183 @default.
- W1980858359 cites W2063550907 @default.
- W1980858359 cites W2065400041 @default.
- W1980858359 cites W2065955021 @default.
- W1980858359 cites W2067749638 @default.
- W1980858359 cites W2068023049 @default.
- W1980858359 cites W2071027962 @default.
- W1980858359 cites W2072124849 @default.
- W1980858359 cites W2073029290 @default.
- W1980858359 cites W2074766231 @default.
- W1980858359 cites W2075978590 @default.
- W1980858359 cites W2079481424 @default.
- W1980858359 cites W2081779304 @default.
- W1980858359 cites W2082748042 @default.
- W1980858359 cites W2084572074 @default.
- W1980858359 cites W2085842281 @default.
- W1980858359 cites W2085875957 @default.
- W1980858359 cites W2097154067 @default.
- W1980858359 cites W2102142826 @default.
- W1980858359 cites W2111097182 @default.
- W1980858359 cites W2116835281 @default.
- W1980858359 cites W2117326605 @default.
- W1980858359 cites W2118149626 @default.
- W1980858359 cites W2119087222 @default.
- W1980858359 cites W2120591817 @default.
- W1980858359 cites W2124086093 @default.
- W1980858359 cites W2124696441 @default.
- W1980858359 cites W2128335946 @default.
- W1980858359 cites W2134292910 @default.
- W1980858359 cites W2135221251 @default.
- W1980858359 cites W2136906469 @default.
- W1980858359 cites W2141987243 @default.
- W1980858359 cites W2143990576 @default.
- W1980858359 cites W2146129300 @default.
- W1980858359 cites W2156112012 @default.
- W1980858359 cites W2159148681 @default.
- W1980858359 cites W2162980328 @default.