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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980865087> ?p ?o ?g. }

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• W1980865087 abstract "Investigation of a DCM extract of the bark of Pleiogynium timoriense from the former Merck collection of natural product extracts for antiproliferative activity indicated that it was active with an IC50 value of 1.3 μg/mL against the A2780 ovarian cancer cell line. Bioassay-directed fractionation of this extract yielded the three new bioactive trihydroxyalkylcyclohexenones 1-3. Their structures were determined by a combination of spectroscopic and chemical methods. Compounds 1-3 exhibited submicromolar antiproliferative activity against the A2780 human ovarian cancer cell line, with IC50 values of 0.8, 0.7, and 0.8 μM, respectively." @default.
• W1980865087 created "2016-06-24" @default.
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• W1980865087 date "2015-07-01" @default.
• W1980865087 modified "2023-10-13" @default.
• W1980865087 title "Antiproliferative Trihydroxyalkylcyclohexenones from <i>Pleiogynium timoriense</i>" @default.
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• W1980865087 doi "https://doi.org/10.1021/acs.jnatprod.5b00119" @default.
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