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- W1980988641 abstract "Abstract SURGICAL removal of the bursa of Fabricius (BF), a lympho-epithelial organ of birds, or chemical suppression of the bursa during embryonic development will markedly reduce or eliminate the bird’s ability to produce circulating antibody, Glick (1964). The bursa of Fabricius may be directly or indirectly involved in antibody production, Glick (1960), Isakovic et al. (1963), and Mueller et al. (1962). We have injected cell suspensions or homogenates of BF into bursaless chicks in an attempt to restore the antibody producing system of the chicken. Some of the chicks inoculated with the BF suspension or homogenate died within several minutes after inoculation. The symptoms produced by the inoculation were severe panting, coughing, tracheal rattling, defecation, drowsiness, feather fluffing, and squawking. These symptoms are similar to the anaphylactic response of chickens to bovine serum albumin, Makinodan et al. (1952). Additional experiments were undertaken to determine the reason for the fatal and anaphylactoid…" @default.
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- W1980988641 date "1965-11-01" @default.
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- W1980988641 title "Anaphylactoid Response Induced by a Single Injection of the Bursa of Fabricius ," @default.
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- W1980988641 doi "https://doi.org/10.3382/ps.0441572" @default.
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