FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980989869> ?p ?o ?g. }

• W1980989869 endingPage "40" @default.
• W1980989869 startingPage "26" @default.
• W1980989869 abstract "Frequency-domain photon migration (FDPM) is a non-invasive optical technique that utilizes intensity-modulated, near-infrared (NIR) light to quantitatively measure optical properties in thick tissues. Optical properties (absorption, mu(a), and scattering, mu(s)', parameters) derived from FDPM measurements can be used to construct low-resolution (0.5 to 1 cm) functional images of tissue hemoglobin (total, oxy-, and deoxy-forms), oxygen saturation, blood volume fraction, water content, fat content and cellular structure. Unlike conventional NIR transillumination, FDPM enables quantitative analysis of tissue absorption and scattering parameters in a single non-invasive measurement. The unique functional information provided by FDPM makes it well-suited to characterizing tumors in thick tissues. In order to test the sensitivity of FDPM for cancer diagnosis, we have initiated clinical studies to quantitatively determine normal and malignant breast tissue optical and physiological properties in human subjects. Measurements are performed using a non-invasive, multi-wavelength, diode-laser FDPM device optimized for clinical studies. Results show that ductal carcinomas (invasive and in situ) and benign fibroadenomas exhibit 1.25 to 3-fold higher absorption than normal breast tissue. Within this group, absorption is greatest for measurements obtained from sites of invasive cancer. Optical scattering is approximately 20% greater in pre-menopausal versus post-menopausal subjects due to differences in gland/cell proliferation and collagen/fat content. Spatial variations in tissue scattering reveal the loss of differentiation associated with breast disease progression. Overall, the metabolic demands of hormonal stimulation and tumor growth are detectable using photon migration techniques. Measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development." @default.
• W1980989869 created "2016-06-24" @default.
• W1980989869 creator A5011185575 @default.
• W1980989869 creator A5015656700 @default.
• W1980989869 creator A5031656771 @default.
• W1980989869 creator A5039380574 @default.
• W1980989869 creator A5045231769 @default.
• W1980989869 creator A5052875747 @default.
• W1980989869 creator A5079000588 @default.
• W1980989869 creator A5089055286 @default.
• W1980989869 date "2000-01-01" @default.
• W1980989869 modified "2023-09-23" @default.
• W1980989869 title "Non-Invasive In Vivo Characterization of Breast Tumors Using Photon Migration Spectroscopy" @default.
• W1980989869 cites W1965014434 @default.
• W1980989869 cites W1972222021 @default.
• W1980989869 cites W1972420594 @default.
• W1980989869 cites W1979918456 @default.
• W1980989869 cites W1980285018 @default.
• W1980989869 cites W1982172883 @default.
• W1980989869 cites W1983592067 @default.
• W1980989869 cites W1995467519 @default.
• W1980989869 cites W1997716890 @default.
• W1980989869 cites W1998055482 @default.
• W1980989869 cites W2007451372 @default.
• W1980989869 cites W2007516491 @default.
• W1980989869 cites W2017668600 @default.
• W1980989869 cites W2017896686 @default.
• W1980989869 cites W2020942987 @default.
• W1980989869 cites W2021750959 @default.
• W1980989869 cites W2024449692 @default.
• W1980989869 cites W2028608312 @default.
• W1980989869 cites W2038345290 @default.
• W1980989869 cites W2050756936 @default.
• W1980989869 cites W2050973816 @default.
• W1980989869 cites W2053719874 @default.
• W1980989869 cites W2057654068 @default.
• W1980989869 cites W2058537576 @default.
• W1980989869 cites W2060644682 @default.
• W1980989869 cites W2065200530 @default.
• W1980989869 cites W2065737799 @default.
• W1980989869 cites W2066057233 @default.
• W1980989869 cites W2077267251 @default.
• W1980989869 cites W2087009179 @default.
• W1980989869 cites W2087051053 @default.
• W1980989869 cites W2091115969 @default.
• W1980989869 cites W2100968199 @default.
• W1980989869 cites W2107958229 @default.
• W1980989869 cites W2109067766 @default.
• W1980989869 cites W2121307183 @default.
• W1980989869 cites W2122155353 @default.
• W1980989869 cites W2134189607 @default.
• W1980989869 cites W2134269165 @default.
• W1980989869 cites W2137523819 @default.
• W1980989869 cites W2152838302 @default.
• W1980989869 cites W2169119609 @default.
• W1980989869 cites W2169242737 @default.
• W1980989869 doi "https://doi.org/10.1038/sj.neo.7900082" @default.
• W1980989869 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1531865" @default.
• W1980989869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10933066" @default.
• W1980989869 hasPublicationYear "2000" @default.
• W1980989869 type Work @default.
• W1980989869 sameAs 1980989869 @default.
• W1980989869 citedByCount "629" @default.
• W1980989869 countsByYear W19809898692012 @default.
• W1980989869 countsByYear W19809898692013 @default.
• W1980989869 countsByYear W19809898692014 @default.
• W1980989869 countsByYear W19809898692015 @default.
• W1980989869 countsByYear W19809898692016 @default.
• W1980989869 countsByYear W19809898692017 @default.
• W1980989869 countsByYear W19809898692018 @default.
• W1980989869 countsByYear W19809898692019 @default.
• W1980989869 countsByYear W19809898692020 @default.
• W1980989869 countsByYear W19809898692021 @default.
• W1980989869 countsByYear W19809898692022 @default.
• W1980989869 countsByYear W19809898692023 @default.
• W1980989869 crossrefType "journal-article" @default.
• W1980989869 hasAuthorship W1980989869A5011185575 @default.
• W1980989869 hasAuthorship W1980989869A5015656700 @default.
• W1980989869 hasAuthorship W1980989869A5031656771 @default.
• W1980989869 hasAuthorship W1980989869A5039380574 @default.
• W1980989869 hasAuthorship W1980989869A5045231769 @default.
• W1980989869 hasAuthorship W1980989869A5052875747 @default.
• W1980989869 hasAuthorship W1980989869A5079000588 @default.
• W1980989869 hasAuthorship W1980989869A5089055286 @default.
• W1980989869 hasBestOaLocation W19809898691 @default.
• W1980989869 hasConcept C120665830 @default.
• W1980989869 hasConcept C121332964 @default.
• W1980989869 hasConcept C125287762 @default.
• W1980989869 hasConcept C142724271 @default.
• W1980989869 hasConcept C185592680 @default.
• W1980989869 hasConcept C191486275 @default.
• W1980989869 hasConcept C192562407 @default.
• W1980989869 hasConcept C46141821 @default.
• W1980989869 hasConcept C71924100 @default.
• W1980989869 hasConceptScore W1980989869C120665830 @default.
• W1980989869 hasConceptScore W1980989869C121332964 @default.
• W1980989869 hasConceptScore W1980989869C125287762 @default.
• W1980989869 hasConceptScore W1980989869C142724271 @default.

• next