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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980995964> ?p ?o ?g. }

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• W1980995964 abstract "We examined the expression of seven V alpha or V beta T cell receptor (TCR) segments on human CD4+ and CD8+ T cells. Confirming previously published results, we found a preferential expression of four V segment gene products on CD4+ T cells. One of these markers (V beta 6.7) was constantly expressed on more CD4+ T cells than CD8+ T cells. None of the analyzed blood samples showed a complete deletion of T cells expressing a particular V beta gene segment. In addition, our data provide the first evidence that genes on sex chromosomes may influence the formation of the human T cell repertoire. The ratio of CD4+/CD8+ T cells expressing V beta 12 gene products was always > or = 1 in female donors, whereas approximately 30% male donors exhibited more CD8+V beta 12+ T cells than CD4+V beta 12+ T cells." @default.
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• W1980995964 date "1993-01-01" @default.
• W1980995964 modified "2023-09-23" @default.
• W1980995964 title "Differential Expression of T Cell Receptor Variable β Genes on CD4+ and CD8+ T Cells: Influence by Sex Linked Genes?" @default.
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• W1980995964 doi "https://doi.org/10.1016/s0171-2985(11)80242-1" @default.
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