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- W1980999858 abstract "The purification of pravastatin, simvastatin and lovastatin in the sodium salt or lactone form and of mevastatin in the lactone form by reversed-phase displacement chromatography is presented. The mobile phases consisted of water or mixtures of water-methanol and water-acetonitrile. Six different displacers were successfully used. Up to 0.14 g of raw sample per gram of stationary phase was loaded on a column packed with silica-based octadecyl phase. Crude substances from 85 to 88% chromatographic purity were purified and at least 99.5% purity was achieved." @default.
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- W1980999858 date "2001-05-01" @default.
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- W1980999858 title "Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors" @default.
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- W1980999858 doi "https://doi.org/10.1016/s0021-9673(01)00767-1" @default.
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