Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981001290> ?p ?o ?g. }
- W1981001290 endingPage "826" @default.
- W1981001290 startingPage "821" @default.
- W1981001290 abstract "Cardiac transcription factors play crucial roles in cardiac development and differentiation. To address the target genes they regulate is important for understanding the molecular mechanisms underlying these processes. In this study, ES cell lines harboring a neomycin resistance gene in the Nkx2–5 gene locus were generated and used to make purified ES cell-derived cardiomyocytes (ESCM) by in vitro differentiation and successive G418 treatment. Three lines with different Nkx2–5 gene expression levels were made and named as Nkx2–5 −/−, +/−, and overexpressing ESCMs. In order to investigate Nkx2–5-regulated gene expression in cardiomyocytes, the gene expression profiles were compared among these lines. The expression patterns of known Nkx2–5 downstream genes were consistent with the previous investigations in vivo. Several genes with Nkx2–5-dependent changes in their expression were detected and confirmed by real-time PCR. This study investigated Nkx2–5-regulated gene expression in ESCM and suggested potential targets of Nkx2–5 in cardiogenesis." @default.
- W1981001290 created "2016-06-24" @default.
- W1981001290 creator A5005311216 @default.
- W1981001290 creator A5009867090 @default.
- W1981001290 creator A5016134558 @default.
- W1981001290 creator A5034347864 @default.
- W1981001290 creator A5042773229 @default.
- W1981001290 creator A5068981310 @default.
- W1981001290 creator A5085128848 @default.
- W1981001290 date "2009-12-01" @default.
- W1981001290 modified "2023-10-16" @default.
- W1981001290 title "The search for Nkx2–5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2–5 gene targeting" @default.
- W1981001290 cites W1970727274 @default.
- W1981001290 cites W1970947849 @default.
- W1981001290 cites W1972662556 @default.
- W1981001290 cites W1973422437 @default.
- W1981001290 cites W1980615784 @default.
- W1981001290 cites W1985130075 @default.
- W1981001290 cites W1988451304 @default.
- W1981001290 cites W2004537703 @default.
- W1981001290 cites W2005435367 @default.
- W1981001290 cites W2016368778 @default.
- W1981001290 cites W2023341510 @default.
- W1981001290 cites W2040489034 @default.
- W1981001290 cites W2043809555 @default.
- W1981001290 cites W2046951940 @default.
- W1981001290 cites W2054913890 @default.
- W1981001290 cites W2069368388 @default.
- W1981001290 cites W2075469935 @default.
- W1981001290 cites W2076600697 @default.
- W1981001290 cites W2078216015 @default.
- W1981001290 cites W2096751146 @default.
- W1981001290 cites W2097355152 @default.
- W1981001290 cites W2106000284 @default.
- W1981001290 cites W2108872905 @default.
- W1981001290 cites W2139707684 @default.
- W1981001290 cites W2147839272 @default.
- W1981001290 cites W2148734937 @default.
- W1981001290 cites W2152814088 @default.
- W1981001290 cites W2170560537 @default.
- W1981001290 cites W2170771909 @default.
- W1981001290 doi "https://doi.org/10.1016/j.bbrc.2009.10.056" @default.
- W1981001290 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19836354" @default.
- W1981001290 hasPublicationYear "2009" @default.
- W1981001290 type Work @default.
- W1981001290 sameAs 1981001290 @default.
- W1981001290 citedByCount "11" @default.
- W1981001290 countsByYear W19810012902013 @default.
- W1981001290 countsByYear W19810012902014 @default.
- W1981001290 countsByYear W19810012902017 @default.
- W1981001290 countsByYear W19810012902022 @default.
- W1981001290 countsByYear W19810012902023 @default.
- W1981001290 crossrefType "journal-article" @default.
- W1981001290 hasAuthorship W1981001290A5005311216 @default.
- W1981001290 hasAuthorship W1981001290A5009867090 @default.
- W1981001290 hasAuthorship W1981001290A5016134558 @default.
- W1981001290 hasAuthorship W1981001290A5034347864 @default.
- W1981001290 hasAuthorship W1981001290A5042773229 @default.
- W1981001290 hasAuthorship W1981001290A5068981310 @default.
- W1981001290 hasAuthorship W1981001290A5085128848 @default.
- W1981001290 hasBestOaLocation W19810012902 @default.
- W1981001290 hasConcept C104317684 @default.
- W1981001290 hasConcept C145103041 @default.
- W1981001290 hasConcept C148738053 @default.
- W1981001290 hasConcept C150194340 @default.
- W1981001290 hasConcept C153911025 @default.
- W1981001290 hasConcept C165864922 @default.
- W1981001290 hasConcept C54355233 @default.
- W1981001290 hasConcept C81885089 @default.
- W1981001290 hasConcept C84597430 @default.
- W1981001290 hasConcept C86339819 @default.
- W1981001290 hasConcept C86803240 @default.
- W1981001290 hasConcept C95444343 @default.
- W1981001290 hasConceptScore W1981001290C104317684 @default.
- W1981001290 hasConceptScore W1981001290C145103041 @default.
- W1981001290 hasConceptScore W1981001290C148738053 @default.
- W1981001290 hasConceptScore W1981001290C150194340 @default.
- W1981001290 hasConceptScore W1981001290C153911025 @default.
- W1981001290 hasConceptScore W1981001290C165864922 @default.
- W1981001290 hasConceptScore W1981001290C54355233 @default.
- W1981001290 hasConceptScore W1981001290C81885089 @default.
- W1981001290 hasConceptScore W1981001290C84597430 @default.
- W1981001290 hasConceptScore W1981001290C86339819 @default.
- W1981001290 hasConceptScore W1981001290C86803240 @default.
- W1981001290 hasConceptScore W1981001290C95444343 @default.
- W1981001290 hasFunder F4320320912 @default.
- W1981001290 hasIssue "3" @default.
- W1981001290 hasLocation W19810012901 @default.
- W1981001290 hasLocation W19810012902 @default.
- W1981001290 hasLocation W19810012903 @default.
- W1981001290 hasOpenAccess W1981001290 @default.
- W1981001290 hasPrimaryLocation W19810012901 @default.
- W1981001290 hasRelatedWork W1886625688 @default.
- W1981001290 hasRelatedWork W2028087115 @default.
- W1981001290 hasRelatedWork W2057739827 @default.
- W1981001290 hasRelatedWork W2074557265 @default.
- W1981001290 hasRelatedWork W2082451158 @default.
- W1981001290 hasRelatedWork W2104498991 @default.