FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981007002> ?p ?o ?g. }

• W1981007002 endingPage "679" @default.
• W1981007002 startingPage "669" @default.
• W1981007002 abstract "The in vitro effect of gamma interferon (IFN-gamma) on nitric oxide (NO) production in a mouse CD5+ B1-like cell line, TH2.52, was studied. The TH2.52 cell line is the hybridoma line between mouse B lymphoma line and mouse splenic B cells and expresses a series of B1 markers. IFN-gamma induced a marked NO production in TH2.52 cells through the expression of an inducible type of NO synthase (iNOS). IFN-gamma-induced NO production was triggered by the Janus tyrosine kinase (JAK)/signal transducer and activator of transcription (STAT) pathway since it was inhibited by AG490, a JAK2 inhibitor. The growth of TH2.52 cells significantly was inhibited in the presence of IFN-gamma. A significant number of cells underwent apoptotic cell death, accompanied by the DNA fragmentation, annexin V binding, and caspase 3 activation. N(G)-monomethyl-L-arginine, an iNOS inhibitor, prevented IFN-gamma-induced cell death. Therefore, IFN-gamma-induced NO production was possible in causing cell death in TH2.52 cells. Further, IFN-gamma-induced NO production and cell death significantly were prevented by interleukin-4, a representative Th2 cytokine. The immunological significance of IFN-gamma-induced NO production in a mouse B1-like cell line is discussed." @default.
• W1981007002 created "2016-06-24" @default.
• W1981007002 creator A5052572084 @default.
• W1981007002 creator A5065718822 @default.
• W1981007002 creator A5071458791 @default.
• W1981007002 creator A5073661988 @default.
• W1981007002 creator A5075168214 @default.
• W1981007002 creator A5077757855 @default.
• W1981007002 creator A5091877740 @default.
• W1981007002 date "2003-09-01" @default.
• W1981007002 modified "2023-10-03" @default.
• W1981007002 title "Gamma Interferon-Induced Nitric Oxide Production in Mouse CD5+B1-Like Cell Line and Its Association with Apoptotic Cell Death" @default.
• W1981007002 cites W1495960032 @default.
• W1981007002 cites W1507400599 @default.
• W1981007002 cites W1512765879 @default.
• W1981007002 cites W1557338648 @default.
• W1981007002 cites W1594149218 @default.
• W1981007002 cites W1605085109 @default.
• W1981007002 cites W1821918060 @default.
• W1981007002 cites W1834041853 @default.
• W1981007002 cites W1902283204 @default.
• W1981007002 cites W1942214720 @default.
• W1981007002 cites W1983588728 @default.
• W1981007002 cites W1985509751 @default.
• W1981007002 cites W1988712438 @default.
• W1981007002 cites W1990802251 @default.
• W1981007002 cites W2011237115 @default.
• W1981007002 cites W2012191233 @default.
• W1981007002 cites W2012451275 @default.
• W1981007002 cites W2015839427 @default.
• W1981007002 cites W2024650410 @default.
• W1981007002 cites W2029275361 @default.
• W1981007002 cites W2037061225 @default.
• W1981007002 cites W2049670306 @default.
• W1981007002 cites W2053120116 @default.
• W1981007002 cites W2077384365 @default.
• W1981007002 cites W2080583113 @default.
• W1981007002 cites W2099898722 @default.
• W1981007002 cites W2106788385 @default.
• W1981007002 cites W2113151375 @default.
• W1981007002 cites W2117775564 @default.
• W1981007002 cites W2121282237 @default.
• W1981007002 cites W2138088212 @default.
• W1981007002 cites W2139537612 @default.
• W1981007002 cites W2149200346 @default.
• W1981007002 cites W2154122218 @default.
• W1981007002 cites W2162532663 @default.
• W1981007002 cites W2196799556 @default.
• W1981007002 cites W2323139294 @default.
• W1981007002 cites W2325707043 @default.
• W1981007002 doi "https://doi.org/10.1111/j.1348-0421.2003.tb03430.x" @default.
• W1981007002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14584614" @default.
• W1981007002 hasPublicationYear "2003" @default.
• W1981007002 type Work @default.
• W1981007002 sameAs 1981007002 @default.
• W1981007002 citedByCount "19" @default.
• W1981007002 countsByYear W19810070022012 @default.
• W1981007002 countsByYear W19810070022013 @default.
• W1981007002 countsByYear W19810070022014 @default.
• W1981007002 countsByYear W19810070022016 @default.
• W1981007002 countsByYear W19810070022017 @default.
• W1981007002 crossrefType "journal-article" @default.
• W1981007002 hasAuthorship W1981007002A5052572084 @default.
• W1981007002 hasAuthorship W1981007002A5065718822 @default.
• W1981007002 hasAuthorship W1981007002A5071458791 @default.
• W1981007002 hasAuthorship W1981007002A5073661988 @default.
• W1981007002 hasAuthorship W1981007002A5075168214 @default.
• W1981007002 hasAuthorship W1981007002A5077757855 @default.
• W1981007002 hasAuthorship W1981007002A5091877740 @default.
• W1981007002 hasConcept C134018914 @default.
• W1981007002 hasConcept C153911025 @default.
• W1981007002 hasConcept C171958077 @default.
• W1981007002 hasConcept C190283241 @default.
• W1981007002 hasConcept C203014093 @default.
• W1981007002 hasConcept C2777622882 @default.
• W1981007002 hasConcept C2778690821 @default.
• W1981007002 hasConcept C2778923194 @default.
• W1981007002 hasConcept C2780841837 @default.
• W1981007002 hasConcept C2908937200 @default.
• W1981007002 hasConcept C31573885 @default.
• W1981007002 hasConcept C502942594 @default.
• W1981007002 hasConcept C519581460 @default.
• W1981007002 hasConcept C54355233 @default.
• W1981007002 hasConcept C55493867 @default.
• W1981007002 hasConcept C81885089 @default.
• W1981007002 hasConcept C86803240 @default.
• W1981007002 hasConceptScore W1981007002C134018914 @default.
• W1981007002 hasConceptScore W1981007002C153911025 @default.
• W1981007002 hasConceptScore W1981007002C171958077 @default.
• W1981007002 hasConceptScore W1981007002C190283241 @default.
• W1981007002 hasConceptScore W1981007002C203014093 @default.
• W1981007002 hasConceptScore W1981007002C2777622882 @default.
• W1981007002 hasConceptScore W1981007002C2778690821 @default.
• W1981007002 hasConceptScore W1981007002C2778923194 @default.
• W1981007002 hasConceptScore W1981007002C2780841837 @default.
• W1981007002 hasConceptScore W1981007002C2908937200 @default.
• W1981007002 hasConceptScore W1981007002C31573885 @default.
• W1981007002 hasConceptScore W1981007002C502942594 @default.

• next