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• W1981014781 abstract "Branched DNA structures play critical roles in DNA replication, repair, and recombination in addition to being key building blocks for DNA nanotechnology. Here we combine single-molecule multiparameter fluorescence detection and molecular dynamics simulations to give a general approach to global structure determination of branched DNA in solution. We reveal an open, planar structure of a forked DNA molecule with three duplex arms and demonstrate an ion-induced conformational change. This structure will serve as a benchmark for DNA-protein interaction studies." @default.
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• W1981014781 date "2010-12-21" @default.
• W1981014781 modified "2023-10-16" @default.
• W1981014781 title "Global Structure of Forked DNA in Solution Revealed by High-Resolution Single-Molecule FRET" @default.
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• W1981014781 doi "https://doi.org/10.1021/ja108626w" @default.
• W1981014781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21174398" @default.
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