FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981015093> ?p ?o ?g. }

• W1981015093 endingPage "1066" @default.
• W1981015093 startingPage "1058" @default.
• W1981015093 abstract "Abstract The pre‐Bötzinger complex (preBötC) in the ventrolateral medulla is thought to be the kernel for respiratory rhythm generation. Neurons in the preBötC contain intense neurokinin‐1 receptor (NK1R) immunoreactivity. Some of these neurons in the adult preBötC are presumed to be the pre‐inspiratory interneurons that are essential for generating respiratory rhythm in the neonate. Chloride‐mediated synaptic inhibition is critical for rhythmogenesis in the adult. The present study used immunofluorescence histochemistry and immunogold‐silver staining to determine the inhibitory synaptic relationship between glutamic acid decarboxylase (GAD)‐ or glycine transporter 2 (GlyT2)‐immunoreactive (ir) boutons and NK1R‐ir neurons in the preBötC of adult rats. Under the confocal microscope, we found that GAD‐ and GlyT2‐ir boutons were in close apposition to NK1R‐ir somas and dendrites in the preBötC. Under the electron microscope, GAD‐ and GlyT2‐ir terminals were in close apposition to NK1R‐ir somas and dendrites. Symmetric synapses were identified between GAD‐ or GlyT2‐ir terminals and NK1R‐ir neurons. A total of 51.6% GAD‐ir and 38.2% GlyT2‐ir terminals were found to contact or make synapses with NK1R‐ir profiles, respectively. GAD‐ and GlyT2‐ir terminals synapsed not only upon NK1R‐ir neurons but also upon NK1R immuno‐negative neurons. NK1R‐ir neurons received both symmetric (presumed inhibitory) and asymmetric (presumed excitatory) synapses. Thus, the present findings provide the morphological basis for inhibitory inputs to NK1R‐ir neurons in the preBötC, consistent with the suggestion that chloride‐mediated synaptic inhibition may contribute importantly to rhythm generation by controlling the membrane potential trajectory and resetting rhythmic bursting of the kernel neurons in the adult." @default.
• W1981015093 created "2016-06-24" @default.
• W1981015093 creator A5003581530 @default.
• W1981015093 creator A5003769106 @default.
• W1981015093 creator A5021511160 @default.
• W1981015093 creator A5025222122 @default.
• W1981015093 creator A5031519477 @default.
• W1981015093 creator A5053646636 @default.
• W1981015093 creator A5056723526 @default.
• W1981015093 date "2002-09-01" @default.
• W1981015093 modified "2023-10-15" @default.
• W1981015093 title "GABAergic and glycinergic synapses onto neurokinin-1 receptor-immunoreactive neurons in the pre-Bötzinger complex of rats: light and electron microscopic studies" @default.
• W1981015093 cites W1536686934 @default.
• W1981015093 cites W1560498709 @default.
• W1981015093 cites W1578558352 @default.
• W1981015093 cites W1791522543 @default.
• W1981015093 cites W1940618937 @default.
• W1981015093 cites W1957270349 @default.
• W1981015093 cites W1969716249 @default.
• W1981015093 cites W1975411099 @default.
• W1981015093 cites W1976416612 @default.
• W1981015093 cites W1980021607 @default.
• W1981015093 cites W1990133063 @default.
• W1981015093 cites W2000744528 @default.
• W1981015093 cites W2025891499 @default.
• W1981015093 cites W2029338036 @default.
• W1981015093 cites W2035049677 @default.
• W1981015093 cites W2035585061 @default.
• W1981015093 cites W2037233574 @default.
• W1981015093 cites W2037688283 @default.
• W1981015093 cites W2039707187 @default.
• W1981015093 cites W2042571545 @default.
• W1981015093 cites W2048304597 @default.
• W1981015093 cites W2069344808 @default.
• W1981015093 cites W2081474897 @default.
• W1981015093 cites W2082997385 @default.
• W1981015093 cites W2103479712 @default.
• W1981015093 cites W2105585258 @default.
• W1981015093 cites W2117770051 @default.
• W1981015093 cites W2118064464 @default.
• W1981015093 cites W2126376455 @default.
• W1981015093 cites W2127687530 @default.
• W1981015093 cites W2130568882 @default.
• W1981015093 cites W2144121601 @default.
• W1981015093 cites W2149464494 @default.
• W1981015093 cites W2159395955 @default.
• W1981015093 cites W2220903811 @default.
• W1981015093 cites W2261288281 @default.
• W1981015093 cites W2748123803 @default.
• W1981015093 doi "https://doi.org/10.1046/j.1460-9568.2002.02163.x" @default.
• W1981015093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12383234" @default.
• W1981015093 hasPublicationYear "2002" @default.
• W1981015093 type Work @default.
• W1981015093 sameAs 1981015093 @default.
• W1981015093 citedByCount "25" @default.
• W1981015093 countsByYear W19810150932012 @default.
• W1981015093 countsByYear W19810150932013 @default.
• W1981015093 countsByYear W19810150932014 @default.
• W1981015093 countsByYear W19810150932015 @default.
• W1981015093 countsByYear W19810150932016 @default.
• W1981015093 countsByYear W19810150932021 @default.
• W1981015093 crossrefType "journal-article" @default.
• W1981015093 hasAuthorship W1981015093A5003581530 @default.
• W1981015093 hasAuthorship W1981015093A5003769106 @default.
• W1981015093 hasAuthorship W1981015093A5021511160 @default.
• W1981015093 hasAuthorship W1981015093A5025222122 @default.
• W1981015093 hasAuthorship W1981015093A5031519477 @default.
• W1981015093 hasAuthorship W1981015093A5053646636 @default.
• W1981015093 hasAuthorship W1981015093A5056723526 @default.
• W1981015093 hasConcept C118303440 @default.
• W1981015093 hasConcept C12554922 @default.
• W1981015093 hasConcept C137130169 @default.
• W1981015093 hasConcept C169760540 @default.
• W1981015093 hasConcept C170493617 @default.
• W1981015093 hasConcept C17077164 @default.
• W1981015093 hasConcept C185592680 @default.
• W1981015093 hasConcept C2776533618 @default.
• W1981015093 hasConcept C2778110749 @default.
• W1981015093 hasConcept C529278444 @default.
• W1981015093 hasConcept C55493867 @default.
• W1981015093 hasConcept C86803240 @default.
• W1981015093 hasConceptScore W1981015093C118303440 @default.
• W1981015093 hasConceptScore W1981015093C12554922 @default.
• W1981015093 hasConceptScore W1981015093C137130169 @default.
• W1981015093 hasConceptScore W1981015093C169760540 @default.
• W1981015093 hasConceptScore W1981015093C170493617 @default.
• W1981015093 hasConceptScore W1981015093C17077164 @default.
• W1981015093 hasConceptScore W1981015093C185592680 @default.
• W1981015093 hasConceptScore W1981015093C2776533618 @default.
• W1981015093 hasConceptScore W1981015093C2778110749 @default.
• W1981015093 hasConceptScore W1981015093C529278444 @default.
• W1981015093 hasConceptScore W1981015093C55493867 @default.
• W1981015093 hasConceptScore W1981015093C86803240 @default.
• W1981015093 hasIssue "6" @default.
• W1981015093 hasLocation W19810150931 @default.
• W1981015093 hasLocation W19810150932 @default.
• W1981015093 hasOpenAccess W1981015093 @default.
• W1981015093 hasPrimaryLocation W19810150931 @default.

• next