Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981058840> ?p ?o ?g. }
- W1981058840 endingPage "273" @default.
- W1981058840 startingPage "270" @default.
- W1981058840 abstract "Objective: Proteins can undergo numerous covalent changes on exposure to oxidants. Oxidative modification of protein in vivo may affect a variety of cellular functions. Protein oxidation in vivo is a natural consequence of aerobic life. Oxygen radicals and other activated oxygen species generated as byproducts of cellular metabolism or from environmental sources cause modifications to the amino acids of proteins that generally result in loss of protein function/enzymatic activity. It is now well known that reactive oxygen species (ROS) play a key role in human cancer development. Moreover, the brain is especially vulnerable to ROS mediated injury. Method: Therefore, in the present study, protein oxidation was assessed in the plasma of 17 patients with brain tumors and 16 age and gender-matched controls by measuring protein thiols and protein carbonyls spectrophotometrically. Results: There was a significant decrease in protein thiols and carbonyls in malignant cases of brain tumors when compared with the control group. No significant change in protein thiols was noted in benign cases compared to controls. A comparison of levels in benign and malignant cases for both the parameters also showed no significant difference. Discussion: Thus, free radical toxicity does lead to protein oxidation in patients with brain tumors." @default.
- W1981058840 created "2016-06-24" @default.
- W1981058840 creator A5013838077 @default.
- W1981058840 creator A5024705858 @default.
- W1981058840 creator A5032944038 @default.
- W1981058840 creator A5039341724 @default.
- W1981058840 creator A5045766679 @default.
- W1981058840 creator A5064710035 @default.
- W1981058840 creator A5084095371 @default.
- W1981058840 creator A5084180097 @default.
- W1981058840 date "2009-04-01" @default.
- W1981058840 modified "2023-10-18" @default.
- W1981058840 title "Plasma protein oxidation in patients with brain tumors" @default.
- W1981058840 cites W1009594272 @default.
- W1981058840 cites W1163687489 @default.
- W1981058840 cites W1512705089 @default.
- W1981058840 cites W1566636169 @default.
- W1981058840 cites W1759706356 @default.
- W1981058840 cites W1828605086 @default.
- W1981058840 cites W1972958434 @default.
- W1981058840 cites W1975278537 @default.
- W1981058840 cites W1978899573 @default.
- W1981058840 cites W1981361599 @default.
- W1981058840 cites W1987741979 @default.
- W1981058840 cites W1995374771 @default.
- W1981058840 cites W2000721848 @default.
- W1981058840 cites W2003166794 @default.
- W1981058840 cites W2006370393 @default.
- W1981058840 cites W2011448179 @default.
- W1981058840 cites W2024555871 @default.
- W1981058840 cites W2031987411 @default.
- W1981058840 cites W2033381823 @default.
- W1981058840 cites W2037116841 @default.
- W1981058840 cites W2043044803 @default.
- W1981058840 cites W2046998110 @default.
- W1981058840 cites W2050000125 @default.
- W1981058840 cites W2074643484 @default.
- W1981058840 cites W2075428562 @default.
- W1981058840 cites W2082184369 @default.
- W1981058840 cites W2082294005 @default.
- W1981058840 cites W2082886469 @default.
- W1981058840 cites W2089772634 @default.
- W1981058840 cites W2090020694 @default.
- W1981058840 cites W2103120039 @default.
- W1981058840 cites W2138368237 @default.
- W1981058840 cites W2141703975 @default.
- W1981058840 cites W2155854925 @default.
- W1981058840 cites W2164066515 @default.
- W1981058840 cites W2166218864 @default.
- W1981058840 cites W2206814260 @default.
- W1981058840 cites W2282794693 @default.
- W1981058840 cites W2415495251 @default.
- W1981058840 cites W4235517036 @default.
- W1981058840 cites W4245957869 @default.
- W1981058840 cites W96985325 @default.
- W1981058840 doi "https://doi.org/10.1179/174313209x382296" @default.
- W1981058840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19040803" @default.
- W1981058840 hasPublicationYear "2009" @default.
- W1981058840 type Work @default.
- W1981058840 sameAs 1981058840 @default.
- W1981058840 citedByCount "6" @default.
- W1981058840 countsByYear W19810588402012 @default.
- W1981058840 countsByYear W19810588402013 @default.
- W1981058840 countsByYear W19810588402022 @default.
- W1981058840 crossrefType "journal-article" @default.
- W1981058840 hasAuthorship W1981058840A5013838077 @default.
- W1981058840 hasAuthorship W1981058840A5024705858 @default.
- W1981058840 hasAuthorship W1981058840A5032944038 @default.
- W1981058840 hasAuthorship W1981058840A5039341724 @default.
- W1981058840 hasAuthorship W1981058840A5045766679 @default.
- W1981058840 hasAuthorship W1981058840A5064710035 @default.
- W1981058840 hasAuthorship W1981058840A5084095371 @default.
- W1981058840 hasAuthorship W1981058840A5084180097 @default.
- W1981058840 hasConcept C139066938 @default.
- W1981058840 hasConcept C150903083 @default.
- W1981058840 hasConcept C178790620 @default.
- W1981058840 hasConcept C181199279 @default.
- W1981058840 hasConcept C185592680 @default.
- W1981058840 hasConcept C202751555 @default.
- W1981058840 hasConcept C207001950 @default.
- W1981058840 hasConcept C2776151105 @default.
- W1981058840 hasConcept C2911203004 @default.
- W1981058840 hasConcept C29730261 @default.
- W1981058840 hasConcept C3020296196 @default.
- W1981058840 hasConcept C48349386 @default.
- W1981058840 hasConcept C515207424 @default.
- W1981058840 hasConcept C55493867 @default.
- W1981058840 hasConcept C57600042 @default.
- W1981058840 hasConcept C62231903 @default.
- W1981058840 hasConcept C86803240 @default.
- W1981058840 hasConceptScore W1981058840C139066938 @default.
- W1981058840 hasConceptScore W1981058840C150903083 @default.
- W1981058840 hasConceptScore W1981058840C178790620 @default.
- W1981058840 hasConceptScore W1981058840C181199279 @default.
- W1981058840 hasConceptScore W1981058840C185592680 @default.
- W1981058840 hasConceptScore W1981058840C202751555 @default.
- W1981058840 hasConceptScore W1981058840C207001950 @default.
- W1981058840 hasConceptScore W1981058840C2776151105 @default.