FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981122460> ?p ?o ?g. }

• W1981122460 endingPage "A94" @default.
• W1981122460 startingPage "A94" @default.
• W1981122460 abstract "The purpose of this study is to investigate the influence of the systemic hemodynamics, plasma renin activity (PRA) and serum concentrations of aldosterone (CA) in the development of left ventricular (LV) geometry in patients with EH. 122 patients with I - III (JNC-VI) (71 men and 51 women, mean age 49.6 ±1.6 years) were examined by 2-D guided M-mode Echocardiography and Radiocardiography with 131I -albumin. PRA and CA were measured by radioimunoassay. Forty-eight normotensive healthy subjects served as controls. Correlation analysis was performed to detect the influence of the hemodynamic and hormonal factors in development of the distinct patterns of LV geometry. Correlation analyses revealed that BP promotes to the development of the LV concentric remodeling. Systolic BP was correlated with posterior wall thickness (PWT) and septal wall thickness (SWT) (r=0.5,P< 0.05; r=0.6, P<0.05, respectively). Diastolic BP was correlated with SWT (r=0.6, P<0.05). Cardiac index (CI) and total peripheral resistance (TPR) were important factors for development of concentric LV hypertrophy (LVH). Correlation analyses revealed that CI was significantly associated with PWT (r=-0.8, P<0.01), SWT (r=-0.7, P<0.01) and LV mass index (LVMI) (r=-0.7, P<0.05). There was found the correlation between the TPR and SWT, and LVMI (r=0.7, P<0.05, each). Pulmonary blood volume (PBV) and circulating blood volume (CBV) play an important role in the development of the eccentric LVH. There was a correlation between PBV and LV end-diastolic diameter (EDD) and LVMI (r=0.8, p<0.001, each) and also between CBV and EDD (r=0.6, P< 0.05) and LVMI (r=0.5, P<0.05). PRA plays an important role for development of concentric LVH. There was observed a correlation between PRA and PWS, SWT (r=0.6, P<0.05, each) and LVMI (r= 0.7, P<0.05). In concentric LVH PRA was significantly increased as compared with normal subjects (nonactive renin 3.1 ± 0.6 vs. 5.3 ±0.3 ng/ml/hr, p< 0.05). CA promotes to the development of the eccentric LVH; there was a correlation with EDD (r=0.5, P<0.05) and LVMI (r=0.6, P<0.05). CA was significantly elevated in patients with eccentric LVH (269.0 ±18.8 vs. 185.0 ± 8.0 ng/ml/hr, P<0.05). Fundamental hemodynamic and hormonal mechanisms of structural adaptation of the LV were established and the concept of multifactoral genesis of LV remodeling was grounded in patients with EH." @default.
• W1981122460 created "2016-06-24" @default.
• W1981122460 creator A5087141125 @default.
• W1981122460 date "2002-04-01" @default.
• W1981122460 modified "2023-09-25" @default.
• W1981122460 title "Extracardiac mechanisms of left ventricular remodeling in essential hypertensive patients" @default.
• W1981122460 doi "https://doi.org/10.1016/s0895-7061(02)02530-x" @default.
• W1981122460 hasPublicationYear "2002" @default.
• W1981122460 type Work @default.
• W1981122460 sameAs 1981122460 @default.
• W1981122460 citedByCount "0" @default.
• W1981122460 crossrefType "journal-article" @default.
• W1981122460 hasAuthorship W1981122460A5087141125 @default.
• W1981122460 hasBestOaLocation W19811224601 @default.
• W1981122460 hasConcept C126322002 @default.
• W1981122460 hasConcept C138976137 @default.
• W1981122460 hasConcept C164705383 @default.
• W1981122460 hasConcept C167414201 @default.
• W1981122460 hasConcept C178853913 @default.
• W1981122460 hasConcept C198710026 @default.
• W1981122460 hasConcept C2776002628 @default.
• W1981122460 hasConcept C2778198053 @default.
• W1981122460 hasConcept C2778525890 @default.
• W1981122460 hasConcept C2779537366 @default.
• W1981122460 hasConcept C57900726 @default.
• W1981122460 hasConcept C71924100 @default.
• W1981122460 hasConcept C84393581 @default.
• W1981122460 hasConceptScore W1981122460C126322002 @default.
• W1981122460 hasConceptScore W1981122460C138976137 @default.
• W1981122460 hasConceptScore W1981122460C164705383 @default.
• W1981122460 hasConceptScore W1981122460C167414201 @default.
• W1981122460 hasConceptScore W1981122460C178853913 @default.
• W1981122460 hasConceptScore W1981122460C198710026 @default.
• W1981122460 hasConceptScore W1981122460C2776002628 @default.
• W1981122460 hasConceptScore W1981122460C2778198053 @default.
• W1981122460 hasConceptScore W1981122460C2778525890 @default.
• W1981122460 hasConceptScore W1981122460C2779537366 @default.
• W1981122460 hasConceptScore W1981122460C57900726 @default.
• W1981122460 hasConceptScore W1981122460C71924100 @default.
• W1981122460 hasConceptScore W1981122460C84393581 @default.
• W1981122460 hasIssue "4" @default.
• W1981122460 hasLocation W19811224601 @default.
• W1981122460 hasOpenAccess W1981122460 @default.
• W1981122460 hasPrimaryLocation W19811224601 @default.
• W1981122460 hasRelatedWork W1990724946 @default.
• W1981122460 hasRelatedWork W2021757858 @default.
• W1981122460 hasRelatedWork W2090448397 @default.
• W1981122460 hasRelatedWork W2149272589 @default.
• W1981122460 hasRelatedWork W2168417210 @default.
• W1981122460 hasRelatedWork W2368322104 @default.
• W1981122460 hasRelatedWork W2408890477 @default.
• W1981122460 hasRelatedWork W2409989216 @default.
• W1981122460 hasRelatedWork W2474901816 @default.
• W1981122460 hasRelatedWork W2610627331 @default.
• W1981122460 hasVolume "15" @default.
• W1981122460 isParatext "false" @default.
• W1981122460 isRetracted "false" @default.
• W1981122460 magId "1981122460" @default.
• W1981122460 workType "article" @default.