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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981124257> ?p ?o ?g. }

• W1981124257 endingPage "1974" @default.
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• W1981124257 abstract "This protocol describes the reconstruction of biological molecules from the electron micrographs of single particles. Computation here is performed using the image-processing software SPIDER and can be managed using a graphical user interface, termed the SPIDER Reconstruction Engine. Two approaches are described to obtain an initial reconstruction: random-conical tilt and common lines. Once an existing model is available, reference-based alignment can be used, a procedure that can be iterated. Also described is supervised classification, a method to look for homogeneous subsets when multiple known conformations of the molecule may coexist." @default.
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• W1981124257 date "2008-10-30" @default.
• W1981124257 modified "2023-10-14" @default.
• W1981124257 title "SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs" @default.
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• W1981124257 doi "https://doi.org/10.1038/nprot.2008.156" @default.
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