Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981125810> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1981125810 abstract "The (S) and (R)-[ 123 I]iodinated analogues of the benzodiazepine receptor partial agonist bretazenil have been synthesised for study of the central benzodiazepine receptor using SPECT. (S)- and (R)-[ 123 I]iodobretazenil were prepared from the appropriate tin precursors by electrophilic iododestannylation with Na[ 123 I] in the presence of Chloramine-T. The products were purified by semi-preparative reverse-phase HPLC with radiochemical yields of 80% in a total synthesis time of 50 minutes. The specific activity was determined to be greater than 2500 Ci/mmol. The radiochemical and chemical purity assessed by radio-TLC and HPLC were found to be 98%. The enantiomeric purity of the (S) and (R) isomers were greater than 97% as assessed by analytical chiral HPLC analysis." @default.
- W1981125810 created "2016-06-24" @default.
- W1981125810 creator A5009783713 @default.
- W1981125810 creator A5033085772 @default.
- W1981125810 creator A5037765698 @default.
- W1981125810 creator A5053518334 @default.
- W1981125810 creator A5065176003 @default.
- W1981125810 creator A5072373299 @default.
- W1981125810 date "1996-09-01" @default.
- W1981125810 modified "2023-10-08" @default.
- W1981125810 title "Synthesis of iodine-123 labelled analogues of the partial agonist (S)- and (R)-bretazenil for the study of CNS benzodiazepine receptors using SPECT" @default.
- W1981125810 cites W1972863088 @default.
- W1981125810 cites W1985900402 @default.
- W1981125810 cites W1989844973 @default.
- W1981125810 cites W2008745330 @default.
- W1981125810 cites W2010774737 @default.
- W1981125810 cites W2011128970 @default.
- W1981125810 cites W2011721366 @default.
- W1981125810 cites W2020419377 @default.
- W1981125810 cites W2046907519 @default.
- W1981125810 cites W2049819189 @default.
- W1981125810 cites W2052591190 @default.
- W1981125810 cites W2073556974 @default.
- W1981125810 cites W2078970852 @default.
- W1981125810 cites W2084906880 @default.
- W1981125810 cites W2095143957 @default.
- W1981125810 cites W2329997802 @default.
- W1981125810 cites W4233959058 @default.
- W1981125810 doi "https://doi.org/10.1002/(sici)1099-1344(199609)38:9<835::aid-jlcr898>3.0.co;2-z" @default.
- W1981125810 hasPublicationYear "1996" @default.
- W1981125810 type Work @default.
- W1981125810 sameAs 1981125810 @default.
- W1981125810 citedByCount "4" @default.
- W1981125810 crossrefType "journal-article" @default.
- W1981125810 hasAuthorship W1981125810A5009783713 @default.
- W1981125810 hasAuthorship W1981125810A5033085772 @default.
- W1981125810 hasAuthorship W1981125810A5037765698 @default.
- W1981125810 hasAuthorship W1981125810A5053518334 @default.
- W1981125810 hasAuthorship W1981125810A5065176003 @default.
- W1981125810 hasAuthorship W1981125810A5072373299 @default.
- W1981125810 hasConcept C170493617 @default.
- W1981125810 hasConcept C179998833 @default.
- W1981125810 hasConcept C185592680 @default.
- W1981125810 hasConcept C2778173252 @default.
- W1981125810 hasConcept C2778938600 @default.
- W1981125810 hasConcept C43617362 @default.
- W1981125810 hasConcept C486523 @default.
- W1981125810 hasConcept C55493867 @default.
- W1981125810 hasConcept C58732023 @default.
- W1981125810 hasConcept C71240020 @default.
- W1981125810 hasConcept C71924100 @default.
- W1981125810 hasConcept C98274493 @default.
- W1981125810 hasConceptScore W1981125810C170493617 @default.
- W1981125810 hasConceptScore W1981125810C179998833 @default.
- W1981125810 hasConceptScore W1981125810C185592680 @default.
- W1981125810 hasConceptScore W1981125810C2778173252 @default.
- W1981125810 hasConceptScore W1981125810C2778938600 @default.
- W1981125810 hasConceptScore W1981125810C43617362 @default.
- W1981125810 hasConceptScore W1981125810C486523 @default.
- W1981125810 hasConceptScore W1981125810C55493867 @default.
- W1981125810 hasConceptScore W1981125810C58732023 @default.
- W1981125810 hasConceptScore W1981125810C71240020 @default.
- W1981125810 hasConceptScore W1981125810C71924100 @default.
- W1981125810 hasConceptScore W1981125810C98274493 @default.
- W1981125810 hasLocation W19811258101 @default.
- W1981125810 hasOpenAccess W1981125810 @default.
- W1981125810 hasPrimaryLocation W19811258101 @default.
- W1981125810 hasRelatedWork W1981263178 @default.
- W1981125810 hasRelatedWork W1993990466 @default.
- W1981125810 hasRelatedWork W1998926788 @default.
- W1981125810 hasRelatedWork W2004045159 @default.
- W1981125810 hasRelatedWork W2009424214 @default.
- W1981125810 hasRelatedWork W2012718293 @default.
- W1981125810 hasRelatedWork W2013222920 @default.
- W1981125810 hasRelatedWork W2036408749 @default.
- W1981125810 hasRelatedWork W2038848153 @default.
- W1981125810 hasRelatedWork W2040879263 @default.
- W1981125810 hasRelatedWork W2048919650 @default.
- W1981125810 hasRelatedWork W2049332029 @default.
- W1981125810 hasRelatedWork W2052539511 @default.
- W1981125810 hasRelatedWork W2065016867 @default.
- W1981125810 hasRelatedWork W2076477385 @default.
- W1981125810 hasRelatedWork W2077553325 @default.
- W1981125810 hasRelatedWork W2084116245 @default.
- W1981125810 hasRelatedWork W2085203673 @default.
- W1981125810 hasRelatedWork W2086317683 @default.
- W1981125810 hasRelatedWork W2093073231 @default.
- W1981125810 isParatext "false" @default.
- W1981125810 isRetracted "false" @default.
- W1981125810 magId "1981125810" @default.
- W1981125810 workType "article" @default.