Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981126988> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1981126988 endingPage "11465" @default.
- W1981126988 startingPage "11460" @default.
- W1981126988 abstract "The 26S proteasome is responsible for the degradation of polyubiquitinated proteins. During this process the polyubiquitin chain is removed. The identity of the proteasomal component that is responsible for this activity has not been clear, as it contains no subunits that resemble known deubiquitinating enzymes. The Jab1/MPN domain is a widespread 120 amino acid protein module found in archaea, bacteria, and eukaryotes. In eukaryotes the Jab1/MPN domain is found in subunits of several multiprotein complexes including the proteasome. Recently it has been proposed that the Jab1/MPN domain of the proteasomal subunit Rpn11 is responsible for the removal of the polyubiquitin chain from substrate proteins. Here we report the crystal structure and characterization of AF2198, a Jab1/MPN domain protein from Archaeoglobolus fulgidus. The structure reveals a fold that resembles that of cytidine deaminase and places the Jab1/MPN domain in a superfamily of metal dependent hydrolases." @default.
- W1981126988 created "2016-06-24" @default.
- W1981126988 creator A5002081980 @default.
- W1981126988 creator A5039263714 @default.
- W1981126988 creator A5062293225 @default.
- W1981126988 creator A5087840496 @default.
- W1981126988 date "2003-09-11" @default.
- W1981126988 modified "2023-10-14" @default.
- W1981126988 title "Structure of the Jab1/MPN Domain and Its Implications for Proteasome Function" @default.
- W1981126988 cites W1530611492 @default.
- W1981126988 cites W1552171878 @default.
- W1981126988 cites W2028231353 @default.
- W1981126988 cites W2101871915 @default.
- W1981126988 cites W2113183492 @default.
- W1981126988 cites W2123781000 @default.
- W1981126988 cites W2166987747 @default.
- W1981126988 doi "https://doi.org/10.1021/bi035033g" @default.
- W1981126988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14516197" @default.
- W1981126988 hasPublicationYear "2003" @default.
- W1981126988 type Work @default.
- W1981126988 sameAs 1981126988 @default.
- W1981126988 citedByCount "118" @default.
- W1981126988 countsByYear W19811269882012 @default.
- W1981126988 countsByYear W19811269882013 @default.
- W1981126988 countsByYear W19811269882014 @default.
- W1981126988 countsByYear W19811269882015 @default.
- W1981126988 countsByYear W19811269882016 @default.
- W1981126988 countsByYear W19811269882017 @default.
- W1981126988 countsByYear W19811269882018 @default.
- W1981126988 countsByYear W19811269882019 @default.
- W1981126988 countsByYear W19811269882020 @default.
- W1981126988 countsByYear W19811269882021 @default.
- W1981126988 countsByYear W19811269882022 @default.
- W1981126988 countsByYear W19811269882023 @default.
- W1981126988 crossrefType "journal-article" @default.
- W1981126988 hasAuthorship W1981126988A5002081980 @default.
- W1981126988 hasAuthorship W1981126988A5039263714 @default.
- W1981126988 hasAuthorship W1981126988A5062293225 @default.
- W1981126988 hasAuthorship W1981126988A5087840496 @default.
- W1981126988 hasConcept C102658986 @default.
- W1981126988 hasConcept C104292427 @default.
- W1981126988 hasConcept C104317684 @default.
- W1981126988 hasConcept C181199279 @default.
- W1981126988 hasConcept C185592680 @default.
- W1981126988 hasConcept C25602115 @default.
- W1981126988 hasConcept C27740335 @default.
- W1981126988 hasConcept C2780120296 @default.
- W1981126988 hasConcept C550995028 @default.
- W1981126988 hasConcept C55493867 @default.
- W1981126988 hasConcept C84982370 @default.
- W1981126988 hasConcept C86803240 @default.
- W1981126988 hasConcept C95444343 @default.
- W1981126988 hasConceptScore W1981126988C102658986 @default.
- W1981126988 hasConceptScore W1981126988C104292427 @default.
- W1981126988 hasConceptScore W1981126988C104317684 @default.
- W1981126988 hasConceptScore W1981126988C181199279 @default.
- W1981126988 hasConceptScore W1981126988C185592680 @default.
- W1981126988 hasConceptScore W1981126988C25602115 @default.
- W1981126988 hasConceptScore W1981126988C27740335 @default.
- W1981126988 hasConceptScore W1981126988C2780120296 @default.
- W1981126988 hasConceptScore W1981126988C550995028 @default.
- W1981126988 hasConceptScore W1981126988C55493867 @default.
- W1981126988 hasConceptScore W1981126988C84982370 @default.
- W1981126988 hasConceptScore W1981126988C86803240 @default.
- W1981126988 hasConceptScore W1981126988C95444343 @default.
- W1981126988 hasIssue "39" @default.
- W1981126988 hasLocation W19811269881 @default.
- W1981126988 hasLocation W19811269882 @default.
- W1981126988 hasOpenAccess W1981126988 @default.
- W1981126988 hasPrimaryLocation W19811269881 @default.
- W1981126988 hasRelatedWork W1689860552 @default.
- W1981126988 hasRelatedWork W1981126988 @default.
- W1981126988 hasRelatedWork W1999761380 @default.
- W1981126988 hasRelatedWork W2014540581 @default.
- W1981126988 hasRelatedWork W2014630160 @default.
- W1981126988 hasRelatedWork W2093700579 @default.
- W1981126988 hasRelatedWork W2209327742 @default.
- W1981126988 hasRelatedWork W3142237605 @default.
- W1981126988 hasRelatedWork W4282555676 @default.
- W1981126988 hasRelatedWork W2387497267 @default.
- W1981126988 hasVolume "42" @default.
- W1981126988 isParatext "false" @default.
- W1981126988 isRetracted "false" @default.
- W1981126988 magId "1981126988" @default.
- W1981126988 workType "article" @default.