Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981148259> ?p ?o ?g. }
- W1981148259 endingPage "88" @default.
- W1981148259 startingPage "80" @default.
- W1981148259 abstract "Abstract Purpose To investigate short‐ and long‐time‐scale 3 He diffusion in asthma. Materials and Methods A hybrid MRI sequence was developed to obtain coregistered short‐ and long‐time‐scale apparent diffusion coefficient (ADC) maps during a single breath‐hold. The study groups were: asthma ( n = 14); healthy ( n = 14); chronic obstructive pulmonary disease (COPD) ( n = 9). Correlations were made between mean‐ADC and %ADC‐abn (abnormal) (%pixels with ADC > mean +2 SD of healthy) at both time scales and spirometry. Sensitivities were determined using receiver operating characteristic (ROC) analysis. Results For asthmatics, the short‐ and long‐time‐scale group‐mean ADCs were 0.254 ± 0.032 cm 2 /s and 0.0237 ± 0.0055 cm 2 /s, respectively, representing a 9% and 27% ( P = 0.038 and P = 0.005) increase compared to the healthy group. The group‐mean %ADC‐abn were 6.4% ± 3.7% and 17.5% ± 14.2%, representing a 107% and 272% ( P = 0.004 and P = 0.006) increase. For COPD much greater elevations were observed. %ADC‐abn provided better discrimination than mean‐ADC between asthmatic and healthy subjects. In asthmatics ADC did not correlate with spirometry. Conclusion With long‐time scale 3 He diffusion magnetic resonance imaging (MRI) changes in lung microstructure were detected in asthma that more conspicuous regionally than at the short time scale. The hybrid diffusion method is a novel means of identifying small airway disease. J. Magn. Reson. Imaging 2008;28:80–88. © 2008 Wiley‐Liss, Inc." @default.
- W1981148259 created "2016-06-24" @default.
- W1981148259 creator A5010396982 @default.
- W1981148259 creator A5015008578 @default.
- W1981148259 creator A5019251773 @default.
- W1981148259 creator A5026508249 @default.
- W1981148259 creator A5032666222 @default.
- W1981148259 creator A5039194767 @default.
- W1981148259 creator A5060305546 @default.
- W1981148259 creator A5063948687 @default.
- W1981148259 creator A5064442260 @default.
- W1981148259 date "2008-06-25" @default.
- W1981148259 modified "2023-10-18" @default.
- W1981148259 title "Assessment of the lung microstructure in patients with asthma using hyperpolarized<sup>3</sup>He diffusion MRI at two time scales: Comparison with healthy subjects and patients with COPD" @default.
- W1981148259 cites W1851957935 @default.
- W1981148259 cites W1968534777 @default.
- W1981148259 cites W1974441898 @default.
- W1981148259 cites W1977093939 @default.
- W1981148259 cites W1982136854 @default.
- W1981148259 cites W1982681786 @default.
- W1981148259 cites W2003129751 @default.
- W1981148259 cites W2006174105 @default.
- W1981148259 cites W2007458765 @default.
- W1981148259 cites W2007995867 @default.
- W1981148259 cites W2012166810 @default.
- W1981148259 cites W2020040017 @default.
- W1981148259 cites W2020361950 @default.
- W1981148259 cites W2023191350 @default.
- W1981148259 cites W2040022821 @default.
- W1981148259 cites W2043268733 @default.
- W1981148259 cites W2047379583 @default.
- W1981148259 cites W2057068290 @default.
- W1981148259 cites W2060515724 @default.
- W1981148259 cites W2085237723 @default.
- W1981148259 cites W2091045687 @default.
- W1981148259 cites W2092874403 @default.
- W1981148259 cites W2097351207 @default.
- W1981148259 cites W2102218823 @default.
- W1981148259 cites W2107347492 @default.
- W1981148259 cites W2112113837 @default.
- W1981148259 cites W2116569033 @default.
- W1981148259 cites W2123257822 @default.
- W1981148259 cites W2124537635 @default.
- W1981148259 cites W2128154647 @default.
- W1981148259 cites W2132564154 @default.
- W1981148259 cites W2133278730 @default.
- W1981148259 cites W2135536493 @default.
- W1981148259 cites W2136002459 @default.
- W1981148259 cites W2139391374 @default.
- W1981148259 cites W2149305542 @default.
- W1981148259 cites W2168384176 @default.
- W1981148259 doi "https://doi.org/10.1002/jmri.21408" @default.
- W1981148259 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2833091" @default.
- W1981148259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18581381" @default.
- W1981148259 hasPublicationYear "2008" @default.
- W1981148259 type Work @default.
- W1981148259 sameAs 1981148259 @default.
- W1981148259 citedByCount "79" @default.
- W1981148259 countsByYear W19811482592012 @default.
- W1981148259 countsByYear W19811482592013 @default.
- W1981148259 countsByYear W19811482592014 @default.
- W1981148259 countsByYear W19811482592015 @default.
- W1981148259 countsByYear W19811482592016 @default.
- W1981148259 countsByYear W19811482592017 @default.
- W1981148259 countsByYear W19811482592018 @default.
- W1981148259 countsByYear W19811482592019 @default.
- W1981148259 countsByYear W19811482592020 @default.
- W1981148259 countsByYear W19811482592021 @default.
- W1981148259 countsByYear W19811482592022 @default.
- W1981148259 countsByYear W19811482592023 @default.
- W1981148259 crossrefType "journal-article" @default.
- W1981148259 hasAuthorship W1981148259A5010396982 @default.
- W1981148259 hasAuthorship W1981148259A5015008578 @default.
- W1981148259 hasAuthorship W1981148259A5019251773 @default.
- W1981148259 hasAuthorship W1981148259A5026508249 @default.
- W1981148259 hasAuthorship W1981148259A5032666222 @default.
- W1981148259 hasAuthorship W1981148259A5039194767 @default.
- W1981148259 hasAuthorship W1981148259A5060305546 @default.
- W1981148259 hasAuthorship W1981148259A5063948687 @default.
- W1981148259 hasAuthorship W1981148259A5064442260 @default.
- W1981148259 hasBestOaLocation W19811482591 @default.
- W1981148259 hasConcept C126322002 @default.
- W1981148259 hasConcept C126838900 @default.
- W1981148259 hasConcept C143409427 @default.
- W1981148259 hasConcept C149550507 @default.
- W1981148259 hasConcept C164705383 @default.
- W1981148259 hasConcept C2776042228 @default.
- W1981148259 hasConcept C2776780178 @default.
- W1981148259 hasConcept C2777714996 @default.
- W1981148259 hasConcept C2780333948 @default.
- W1981148259 hasConcept C2989005 @default.
- W1981148259 hasConcept C58471807 @default.
- W1981148259 hasConcept C70816921 @default.
- W1981148259 hasConcept C71924100 @default.
- W1981148259 hasConceptScore W1981148259C126322002 @default.
- W1981148259 hasConceptScore W1981148259C126838900 @default.
- W1981148259 hasConceptScore W1981148259C143409427 @default.
- W1981148259 hasConceptScore W1981148259C149550507 @default.