Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981192410> ?p ?o ?g. }
- W1981192410 endingPage "186" @default.
- W1981192410 startingPage "179" @default.
- W1981192410 abstract "Tetrahymena thermophila and Paramecium tetraurelia are ciliates that reassign TAA and TAG from stop codons to glutamine codons. Because of the lack of full genome sequences, few studies have concentrated on analyzing the effects of codon reassignment in protein evolution. We used the recently sequenced genome of these species to analyze the patterns of amino acid substitution in ciliates that reassign the code. We show that, as expected, the codon reassignment has a large impact on amino acid substitutions in closely related proteins; however, contrary to expectations, these effects also hold for very diverged proteins. Previous studies have used amino acid substitution data to calculate the minimization of the genetic code; our results show that because of the lasting influence of the code in the patterns of substitution, such studies are tautological. These different substitution patterns might affect alignment of ciliate proteins, as alignment programs use scoring matrices based on substitution patterns of organisms that use the standard code. We also show that glutamine is used more frequently in ciliates than in other species, as often as expected based on the presence of the 2 new reassigned codons, indicating that the frequencies of amino acids in proteomes is mostly determined by neutral processes based on their number of codons." @default.
- W1981192410 created "2016-06-24" @default.
- W1981192410 creator A5068708465 @default.
- W1981192410 creator A5075135655 @default.
- W1981192410 date "2007-11-13" @default.
- W1981192410 modified "2023-09-26" @default.
- W1981192410 title "Consequences of Stop Codon Reassignment on Protein Evolution in Ciliates with Alternative Genetic Codes" @default.
- W1981192410 cites W1502060396 @default.
- W1981192410 cites W1562015000 @default.
- W1981192410 cites W1606746638 @default.
- W1981192410 cites W1871766838 @default.
- W1981192410 cites W1978667203 @default.
- W1981192410 cites W1983519005 @default.
- W1981192410 cites W1983811433 @default.
- W1981192410 cites W1986171929 @default.
- W1981192410 cites W1994912237 @default.
- W1981192410 cites W1999612341 @default.
- W1981192410 cites W2009960889 @default.
- W1981192410 cites W2015292449 @default.
- W1981192410 cites W2017519756 @default.
- W1981192410 cites W2020772746 @default.
- W1981192410 cites W2033177501 @default.
- W1981192410 cites W2045804941 @default.
- W1981192410 cites W2054592804 @default.
- W1981192410 cites W2055043387 @default.
- W1981192410 cites W2055553278 @default.
- W1981192410 cites W2070003197 @default.
- W1981192410 cites W2073076281 @default.
- W1981192410 cites W2090542689 @default.
- W1981192410 cites W2100681850 @default.
- W1981192410 cites W2108494811 @default.
- W1981192410 cites W2118581189 @default.
- W1981192410 cites W2129161084 @default.
- W1981192410 cites W2141279267 @default.
- W1981192410 cites W2143210482 @default.
- W1981192410 cites W2155172429 @default.
- W1981192410 cites W2158714788 @default.
- W1981192410 cites W2163648372 @default.
- W1981192410 cites W2409885542 @default.
- W1981192410 cites W306515700 @default.
- W1981192410 doi "https://doi.org/10.1093/molbev/msm237" @default.
- W1981192410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17974549" @default.
- W1981192410 hasPublicationYear "2007" @default.
- W1981192410 type Work @default.
- W1981192410 sameAs 1981192410 @default.
- W1981192410 citedByCount "13" @default.
- W1981192410 countsByYear W19811924102012 @default.
- W1981192410 countsByYear W19811924102013 @default.
- W1981192410 countsByYear W19811924102016 @default.
- W1981192410 countsByYear W19811924102017 @default.
- W1981192410 countsByYear W19811924102020 @default.
- W1981192410 countsByYear W19811924102021 @default.
- W1981192410 countsByYear W19811924102022 @default.
- W1981192410 crossrefType "journal-article" @default.
- W1981192410 hasAuthorship W1981192410A5068708465 @default.
- W1981192410 hasAuthorship W1981192410A5075135655 @default.
- W1981192410 hasConcept C104317684 @default.
- W1981192410 hasConcept C104397665 @default.
- W1981192410 hasConcept C10853874 @default.
- W1981192410 hasConcept C141231307 @default.
- W1981192410 hasConcept C20580545 @default.
- W1981192410 hasConcept C2777166614 @default.
- W1981192410 hasConcept C2779349466 @default.
- W1981192410 hasConcept C2780536333 @default.
- W1981192410 hasConcept C515207424 @default.
- W1981192410 hasConcept C54355233 @default.
- W1981192410 hasConcept C55493867 @default.
- W1981192410 hasConcept C70721500 @default.
- W1981192410 hasConcept C78458016 @default.
- W1981192410 hasConcept C86803240 @default.
- W1981192410 hasConcept C87253356 @default.
- W1981192410 hasConceptScore W1981192410C104317684 @default.
- W1981192410 hasConceptScore W1981192410C104397665 @default.
- W1981192410 hasConceptScore W1981192410C10853874 @default.
- W1981192410 hasConceptScore W1981192410C141231307 @default.
- W1981192410 hasConceptScore W1981192410C20580545 @default.
- W1981192410 hasConceptScore W1981192410C2777166614 @default.
- W1981192410 hasConceptScore W1981192410C2779349466 @default.
- W1981192410 hasConceptScore W1981192410C2780536333 @default.
- W1981192410 hasConceptScore W1981192410C515207424 @default.
- W1981192410 hasConceptScore W1981192410C54355233 @default.
- W1981192410 hasConceptScore W1981192410C55493867 @default.
- W1981192410 hasConceptScore W1981192410C70721500 @default.
- W1981192410 hasConceptScore W1981192410C78458016 @default.
- W1981192410 hasConceptScore W1981192410C86803240 @default.
- W1981192410 hasConceptScore W1981192410C87253356 @default.
- W1981192410 hasIssue "1" @default.
- W1981192410 hasLocation W19811924101 @default.
- W1981192410 hasLocation W19811924102 @default.
- W1981192410 hasOpenAccess W1981192410 @default.
- W1981192410 hasPrimaryLocation W19811924101 @default.
- W1981192410 hasRelatedWork W1981192410 @default.
- W1981192410 hasRelatedWork W1987274146 @default.
- W1981192410 hasRelatedWork W2028466606 @default.
- W1981192410 hasRelatedWork W2070003197 @default.
- W1981192410 hasRelatedWork W2132060660 @default.
- W1981192410 hasRelatedWork W2136305067 @default.
- W1981192410 hasRelatedWork W2346962335 @default.