FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981194073> ?p ?o ?g. }

• W1981194073 endingPage "202" @default.
• W1981194073 startingPage "189" @default.
• W1981194073 abstract "To characterize interleukin (IL)-5-induced eosinophils, we examined the expression of CD44, very late antigen (VLA)-4, and the IL-5 receptor α chain, as well as the levels of eosinophil peroxidase and the generation of superoxide. Eosinophils were prepared from IL-5-transgenic mice, then characterized using electron microscopy to determine their responses to stimuli. Whereas CD44 densities remained almost constant, the level of VLA-4 increased in parallel with eosinophil maturation. Although a subset of IL-5-induced eosinophils with high side scatter recovered from bone marrow and rare ones found in blood recognized hyaluronic acid (HA), most did not have this property. Bone marrow eosinophils with high side scatter and lower density contained eosinophil peroxidase, not only in granules, but also in membranous structures for 30% of this population. This population developed HA-binding ability in response to IL-3, IL-4, IL-5, granulocyte-macrophage colony-stimulating factor, macrophage inflammatory protein (MIP)-2, monocyte chemotactic protein (MCP)-1, eotaxin, nerve growth factor (NGF), and opsonized zymosan (OZ). Peripheral blood eosinophils acquired HA-binding ability in response to the same stimuli, but their responses were less than those of bone marrow eosinophils with high levels of side scatter. However, splenic eosinophils did not respond to these stimuli. Although peripheral blood eosinophils did not proliferate when stimulated by IL-5, these were the only cells that released eosinophil peroxidase in response to IL-4, MIP-2, MCP-1, eotaxin, NGF, and OZ. With the exception of a subset of bone marrow eosinophils, the ability to acquire HA binding, but not the ability to generate superoxide, correlated with eosinophil peroxidase activity and major basic protein accumulation in the granules of maturing cells." @default.
• W1981194073 created "2016-06-24" @default.
• W1981194073 creator A5005730268 @default.
• W1981194073 creator A5016982418 @default.
• W1981194073 creator A5017757151 @default.
• W1981194073 creator A5018589149 @default.
• W1981194073 creator A5020517072 @default.
• W1981194073 creator A5027370596 @default.
• W1981194073 creator A5048431842 @default.
• W1981194073 creator A5048705945 @default.
• W1981194073 creator A5051259343 @default.
• W1981194073 creator A5051957974 @default.
• W1981194073 creator A5052441689 @default.
• W1981194073 creator A5055461062 @default.
• W1981194073 creator A5068139601 @default.
• W1981194073 creator A5091092096 @default.
• W1981194073 date "2001-04-01" @default.
• W1981194073 modified "2023-10-01" @default.
• W1981194073 title "Differentiation Stages of Eosinophils Characterized by Hyaluronic Acid Binding via CD44 and Responsiveness to Stimuli" @default.
• W1981194073 cites W1533970251 @default.
• W1981194073 cites W1577146075 @default.
• W1981194073 cites W163520811 @default.
• W1981194073 cites W180810881 @default.
• W1981194073 cites W1970901348 @default.
• W1981194073 cites W1973485202 @default.
• W1981194073 cites W1973573706 @default.
• W1981194073 cites W1979116835 @default.
• W1981194073 cites W1995104908 @default.
• W1981194073 cites W2004203577 @default.
• W1981194073 cites W2006696441 @default.
• W1981194073 cites W2006774731 @default.
• W1981194073 cites W2010479839 @default.
• W1981194073 cites W2011723257 @default.
• W1981194073 cites W2018006042 @default.
• W1981194073 cites W2021550524 @default.
• W1981194073 cites W2037663265 @default.
• W1981194073 cites W2040487176 @default.
• W1981194073 cites W2040652964 @default.
• W1981194073 cites W2043027238 @default.
• W1981194073 cites W2049133041 @default.
• W1981194073 cites W2049651574 @default.
• W1981194073 cites W2052068396 @default.
• W1981194073 cites W2058211118 @default.
• W1981194073 cites W2062003642 @default.
• W1981194073 cites W2066802006 @default.
• W1981194073 cites W2071167287 @default.
• W1981194073 cites W2072900152 @default.
• W1981194073 cites W2083977584 @default.
• W1981194073 cites W2084479009 @default.
• W1981194073 cites W2109554295 @default.
• W1981194073 cites W2119289008 @default.
• W1981194073 cites W2136902889 @default.
• W1981194073 cites W2166858952 @default.
• W1981194073 cites W4230976467 @default.
• W1981194073 doi "https://doi.org/10.1089/104454901750219071" @default.
• W1981194073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11403716" @default.
• W1981194073 hasPublicationYear "2001" @default.
• W1981194073 type Work @default.
• W1981194073 sameAs 1981194073 @default.
• W1981194073 citedByCount "15" @default.
• W1981194073 countsByYear W19811940732012 @default.
• W1981194073 countsByYear W19811940732014 @default.
• W1981194073 countsByYear W19811940732018 @default.
• W1981194073 countsByYear W19811940732020 @default.
• W1981194073 crossrefType "journal-article" @default.
• W1981194073 hasAuthorship W1981194073A5005730268 @default.
• W1981194073 hasAuthorship W1981194073A5016982418 @default.
• W1981194073 hasAuthorship W1981194073A5017757151 @default.
• W1981194073 hasAuthorship W1981194073A5018589149 @default.
• W1981194073 hasAuthorship W1981194073A5020517072 @default.
• W1981194073 hasAuthorship W1981194073A5027370596 @default.
• W1981194073 hasAuthorship W1981194073A5048431842 @default.
• W1981194073 hasAuthorship W1981194073A5048705945 @default.
• W1981194073 hasAuthorship W1981194073A5051259343 @default.
• W1981194073 hasAuthorship W1981194073A5051957974 @default.
• W1981194073 hasAuthorship W1981194073A5052441689 @default.
• W1981194073 hasAuthorship W1981194073A5055461062 @default.
• W1981194073 hasAuthorship W1981194073A5068139601 @default.
• W1981194073 hasAuthorship W1981194073A5091092096 @default.
• W1981194073 hasConcept C105702510 @default.
• W1981194073 hasConcept C1491633281 @default.
• W1981194073 hasConcept C153911025 @default.
• W1981194073 hasConcept C162008176 @default.
• W1981194073 hasConcept C181199279 @default.
• W1981194073 hasConcept C202751555 @default.
• W1981194073 hasConcept C203014093 @default.
• W1981194073 hasConcept C2776042228 @default.
• W1981194073 hasConcept C2777037409 @default.
• W1981194073 hasConcept C2777529286 @default.
• W1981194073 hasConcept C2777983669 @default.
• W1981194073 hasConcept C2778081958 @default.
• W1981194073 hasConcept C2779244956 @default.
• W1981194073 hasConcept C2780007613 @default.
• W1981194073 hasConcept C2780932548 @default.
• W1981194073 hasConcept C2908647359 @default.
• W1981194073 hasConcept C55493867 @default.
• W1981194073 hasConcept C60483475 @default.
• W1981194073 hasConcept C71924100 @default.

• next