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- W1981304693 abstract "Testicular biopsy has undergone several modifications during the past 30 years; and with the increasing use of fine needle aspiration (FNA) biopsy, we have seen changes in its indications, technique and interpretation. Currently, there is no agreement on systematic reporting of testicular biopsies. Terms used are not standardized and are often subjective with vague conclusions made in pathology reports. New technological advances and the introduction of intracytoplasmic sperm insemination (ICSI) require pathologists to make an accurate assessment of germ cell development in the testis and to use objective criteria to detect spermatozoa and their precursors whenever present. Prior to the ICSI era, indications for a testicular biopsy were azoospermia and severe oligospermia. With the advent of ICSI, it became evident that obtaining a single sperm would allow an attempt at in vitro fertilization. Azoospermia, therefore, became the only indication for testicular biopsy, whether by traditional tissue sampling or by FNA. A new system of grading is proposed based on FNA, which correlates well with the findings of traditional biopsy as well as with testicular volume and FSH levels; there is also good correlation with clinical outcome in azoospermic males." @default.
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- W1981304693 date "1998-03-01" @default.
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- W1981304693 title "Testicular biopsy: an update" @default.
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- W1981304693 doi "https://doi.org/10.1016/s0968-6053(98)80030-6" @default.
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