Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981306202> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1981306202 endingPage "269" @default.
- W1981306202 startingPage "261" @default.
- W1981306202 abstract "Abstract The purpose of this study was to determine the frequencies of hereditary and familial breast cancers among Lower Silesian women. The questionnaires, dealing with cancer episodes in first-and second-degree relatives, were sent to 5,000 females, who were diagnosed with breast cancer between 1984 and 2005. Twenty-five percent of the questionnaires were completed and returned. Their analysis and further counseling revealed that 24.9% of the responders met the criteria for familial breast cancer (FBC), including 10.5% definitive cases. Mutations in BRCA1 were detected in 32.5% and 1.9% of patients with definitive and suspected FBC, respectively. They all represented three of the abnormalities of the BRCA1 gene: 300T/G, 4153delA and 5382insC. No mutations of BRCA2 were found in material studied. Although a fraction of FBCs identified in our study was similar to those described in other European countries and in the United States, the percentages of genetic mutations seen on routine tests were relatively low. Consequently, the standardized analysis of oncological pedigree seems to be a more valuable diagnostic tool if patients with familial aggregations of breast cancer are targeted in a prophylactic context only." @default.
- W1981306202 created "2016-06-24" @default.
- W1981306202 creator A5021539902 @default.
- W1981306202 creator A5030688867 @default.
- W1981306202 creator A5057400992 @default.
- W1981306202 date "2006-09-01" @default.
- W1981306202 modified "2023-10-15" @default.
- W1981306202 title "Familial and inherited breast cancers in Lower Silesia (Poland)" @default.
- W1981306202 cites W156793033 @default.
- W1981306202 cites W1772785684 @default.
- W1981306202 cites W1907599506 @default.
- W1981306202 cites W1946772620 @default.
- W1981306202 cites W1979368669 @default.
- W1981306202 cites W1990798082 @default.
- W1981306202 cites W2010259315 @default.
- W1981306202 cites W2014813076 @default.
- W1981306202 cites W2030093162 @default.
- W1981306202 cites W2044210218 @default.
- W1981306202 cites W2045667568 @default.
- W1981306202 cites W2055854757 @default.
- W1981306202 cites W2059831284 @default.
- W1981306202 cites W2097026108 @default.
- W1981306202 cites W2104356108 @default.
- W1981306202 cites W2109465247 @default.
- W1981306202 cites W2122443986 @default.
- W1981306202 cites W2138270253 @default.
- W1981306202 cites W2162479847 @default.
- W1981306202 cites W2170137499 @default.
- W1981306202 cites W2615212136 @default.
- W1981306202 cites W4252946660 @default.
- W1981306202 cites W4297672256 @default.
- W1981306202 cites W913577674 @default.
- W1981306202 doi "https://doi.org/10.2478/s11536-006-0022-y" @default.
- W1981306202 hasPublicationYear "2006" @default.
- W1981306202 type Work @default.
- W1981306202 sameAs 1981306202 @default.
- W1981306202 citedByCount "0" @default.
- W1981306202 crossrefType "journal-article" @default.
- W1981306202 hasAuthorship W1981306202A5021539902 @default.
- W1981306202 hasAuthorship W1981306202A5030688867 @default.
- W1981306202 hasAuthorship W1981306202A5057400992 @default.
- W1981306202 hasBestOaLocation W19813062021 @default.
- W1981306202 hasConcept C121608353 @default.
- W1981306202 hasConcept C126322002 @default.
- W1981306202 hasConcept C143998085 @default.
- W1981306202 hasConcept C151730666 @default.
- W1981306202 hasConcept C187212893 @default.
- W1981306202 hasConcept C2779343474 @default.
- W1981306202 hasConcept C2780673598 @default.
- W1981306202 hasConcept C29456083 @default.
- W1981306202 hasConcept C530470458 @default.
- W1981306202 hasConcept C54355233 @default.
- W1981306202 hasConcept C71924100 @default.
- W1981306202 hasConcept C80227256 @default.
- W1981306202 hasConcept C86803240 @default.
- W1981306202 hasConceptScore W1981306202C121608353 @default.
- W1981306202 hasConceptScore W1981306202C126322002 @default.
- W1981306202 hasConceptScore W1981306202C143998085 @default.
- W1981306202 hasConceptScore W1981306202C151730666 @default.
- W1981306202 hasConceptScore W1981306202C187212893 @default.
- W1981306202 hasConceptScore W1981306202C2779343474 @default.
- W1981306202 hasConceptScore W1981306202C2780673598 @default.
- W1981306202 hasConceptScore W1981306202C29456083 @default.
- W1981306202 hasConceptScore W1981306202C530470458 @default.
- W1981306202 hasConceptScore W1981306202C54355233 @default.
- W1981306202 hasConceptScore W1981306202C71924100 @default.
- W1981306202 hasConceptScore W1981306202C80227256 @default.
- W1981306202 hasConceptScore W1981306202C86803240 @default.
- W1981306202 hasIssue "3" @default.
- W1981306202 hasLocation W19813062021 @default.
- W1981306202 hasLocation W19813062022 @default.
- W1981306202 hasOpenAccess W1981306202 @default.
- W1981306202 hasPrimaryLocation W19813062021 @default.
- W1981306202 hasRelatedWork W2017336617 @default.
- W1981306202 hasRelatedWork W2023425329 @default.
- W1981306202 hasRelatedWork W2086235183 @default.
- W1981306202 hasRelatedWork W2123757376 @default.
- W1981306202 hasRelatedWork W2132661220 @default.
- W1981306202 hasRelatedWork W2134377118 @default.
- W1981306202 hasRelatedWork W2417836888 @default.
- W1981306202 hasRelatedWork W3028485698 @default.
- W1981306202 hasRelatedWork W377899687 @default.
- W1981306202 hasRelatedWork W4293229760 @default.
- W1981306202 hasVolume "1" @default.
- W1981306202 isParatext "false" @default.
- W1981306202 isRetracted "false" @default.
- W1981306202 magId "1981306202" @default.
- W1981306202 workType "article" @default.