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- W1981326929 abstract "Abstract In rats treated simultaneously with beta-aminopropionitrile (BAPN) 70 mg/kg and with 300 mg/kg sodium salicylate dose the metabolism of collagen was studied by determining the specific and total activities of 14 C-hydroxyproline in collagen fractions of skin and in urine after the injection of 14 C-proline. BAPN and sodium salicylate was administered daily for 56 days, the 14 C-proline was injected on 28th day of experiment. At the dose used BAPN produced in untreated animals a heavy degree of lathyritic changes with depression of collagen metabolism, and the well known defect manifested by slower conversion of extractable into insoluble collagen. Simultaneous treatment with sodium salicylate resulted in a partial return to normal of these changes, e.g. elevation of metabolic turnover of collagen with faster maturation of collagen." @default.
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- W1981326929 date "1968-08-01" @default.
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- W1981326929 title "The influence of sodium salicylate on the metabolism of collagen in the lathyritic rat" @default.
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- W1981326929 doi "https://doi.org/10.1016/0006-2952(68)90209-8" @default.
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