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• W1981351951 abstract "Aim: We hypothesized that circulating apelin concentrations in preterm babies might be linked with retinopathy of prematurity (ROP), similar to IGF-1 levels. Patients & methods: A total of 97 infants born with a gestational age before 32 weeks in 2007–2009 were screened for ROP at the Gata Haydarpasa Hospital (Turkey). Fourteen of them with classified ROP stage 3–5 comprised our study group. Results: The non-ROP group had higher apelin and IGF-1 levels than ROP neonates at birth. After 4–6 weeks, postnatal ROP subjects had lower apelin and IGF-1 levels than non-ROP controls. At the end of the study, the change in apelin levels was positively correlated with the change in IGF-1 levels (r = 0.852; p = 0.01). Conclusion: We suggested that the pathogenesis of ROP, which is regarded as a neovascular retinal disorder, includes variations in the levels of apelin and IGF-1." @default.
• W1981351951 created "2016-06-24" @default.
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• W1981351951 date "2012-12-01" @default.
• W1981351951 modified "2023-10-16" @default.
• W1981351951 title "Correlation between cord blood apelin and IGF-1 levels in retinopathy of prematurity" @default.
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• W1981351951 doi "https://doi.org/10.2217/bmm.12.82" @default.
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