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• W1981364103 abstract "Organization (WHO) epidemiologist stationed in Vietnam, alerted the global health community to the high transmissibility and lethality associated with an apparently new respiratory disease. This disease, now called severe acute respiratory syndrome (SARS), is believed to have emerged in China in November 2002 and progressed to a global health threat by the spring of 2003 (1–3). On March 15, 2003, with clusters of SARS cases being reported from China, Hong Kong, Vietnam, Singapore, and Canada, WHO issued a global travel alert. At that point, the international health community faced a potential pandemic for which there were no identified causal agent, no diagnostic laboratory assays, no defined properties or risk factors for transmission, no infection-control practices of proven efficacy, and no known treatment or prevention measures. Given that setting, the declaration on July 5 that SARS had been contained (in less than 4 months after its initial recognition), represented a remarkable achievement for a truly extraordinary international public health effort. However, the SARS outbreak was not contained before it had had a substantial impact: 8,098 cases involving 774 deaths were attributed to SARS (4) (the original WHO case definitions [5] were revised during the outbreak to those shown in the Table); fear of contagion was rife in many communities, especially among healthcare workers; and billions of dollars had been lost in the airline and tourism industries, resulting in bankruptcies of airlines and other businesses. However, the SARS public health response effort was equally important: the world’s scientific, clinical, and public health communities had successfully instituted sensitive surveillance for the disease; isolation and infection-control practices—with intensive contact tracing and community containment, including quarantine—were effective in limiting continued spread in most cases; and the causative agent and diagnostic assays for detecting the disease were identified. Now, nearly 1 year after the world first faced this infectious disease challenge, the public health community is equipped with a broader understanding of the agent, its pathophysiology, clinical signs and symptoms, risk factors for transmission, and public health measures that can successfully contain the disease. The breadth of this understanding and international scope of the outbreak response are reflected in the range of manuscript topics in this issue Wresting SARS from Uncertainty" @default.
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• W1981364103 date "2004-02-01" @default.
• W1981364103 modified "2023-09-26" @default.
• W1981364103 title "Wresting SARS from Uncertainty" @default.
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• W1981364103 doi "https://doi.org/10.3201/eid1002.031032" @default.
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