Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981377319> ?p ?o ?g. }
- W1981377319 endingPage "1295" @default.
- W1981377319 startingPage "1286" @default.
- W1981377319 abstract "Aging is a natural, complex, and multifactorial biological process associated with impairment of bioenergetic function, increased oxidative stress, attenuated ability to respond to stresses, and increased risk of contracting age-associated diseases. Oxidative stress is widely thought to underpin many aging processes. The mitochondrion, the powerhouse of the cell, is considered the most important cellular organelle to contribute to the aging process, mainly through respiratory chain dysfunction and formation of reactive oxygen species, leading to damage to mitochondrial proteins, lipids, and mitochondrial DNA. Cardiolipin, a phospholipid located at the level of the inner mitochondrial membrane, is known to be intimately involved in several mitochondrial bioenergetic processes as well as mitochondrial-dependent steps in apoptosis and mitochondrial membrane stability and dynamics. Alterations to cardiolipin structure, content, and acyl chain composition have been associated with mitochondrial dysfunction in multiple tissues in several physiopathological conditions and aging. In this review, we discuss several aspects of mitochondrial bioenergetic alterations in aging and the role played by reactive oxygen species and cardiolipin in these alterations." @default.
- W1981377319 created "2016-06-24" @default.
- W1981377319 creator A5050129876 @default.
- W1981377319 creator A5069357648 @default.
- W1981377319 creator A5078373042 @default.
- W1981377319 creator A5091503559 @default.
- W1981377319 date "2010-05-15" @default.
- W1981377319 modified "2023-09-30" @default.
- W1981377319 title "Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging" @default.
- W1981377319 cites W1000327076 @default.
- W1981377319 cites W1480350120 @default.
- W1981377319 cites W1486525201 @default.
- W1981377319 cites W1488808855 @default.
- W1981377319 cites W1494360569 @default.
- W1981377319 cites W1514650462 @default.
- W1981377319 cites W1528220495 @default.
- W1981377319 cites W1531879407 @default.
- W1981377319 cites W1560423324 @default.
- W1981377319 cites W1565127991 @default.
- W1981377319 cites W1568406795 @default.
- W1981377319 cites W1613536427 @default.
- W1981377319 cites W1838909952 @default.
- W1981377319 cites W1925799544 @default.
- W1981377319 cites W1964991486 @default.
- W1981377319 cites W1965490406 @default.
- W1981377319 cites W1965586048 @default.
- W1981377319 cites W1966429519 @default.
- W1981377319 cites W1967824630 @default.
- W1981377319 cites W1968112618 @default.
- W1981377319 cites W1972666591 @default.
- W1981377319 cites W1973851166 @default.
- W1981377319 cites W1974145389 @default.
- W1981377319 cites W1974396693 @default.
- W1981377319 cites W1977914031 @default.
- W1981377319 cites W1981261838 @default.
- W1981377319 cites W1982577723 @default.
- W1981377319 cites W1982647833 @default.
- W1981377319 cites W1982753455 @default.
- W1981377319 cites W1982928579 @default.
- W1981377319 cites W1984019957 @default.
- W1981377319 cites W1984222168 @default.
- W1981377319 cites W1986248905 @default.
- W1981377319 cites W1987219977 @default.
- W1981377319 cites W1987590284 @default.
- W1981377319 cites W1988058885 @default.
- W1981377319 cites W1988354683 @default.
- W1981377319 cites W1989300887 @default.
- W1981377319 cites W1990536375 @default.
- W1981377319 cites W1990625705 @default.
- W1981377319 cites W1993103335 @default.
- W1981377319 cites W1993149192 @default.
- W1981377319 cites W1993903763 @default.
- W1981377319 cites W1994442108 @default.
- W1981377319 cites W1994496497 @default.
- W1981377319 cites W1999378703 @default.
- W1981377319 cites W1999671103 @default.
- W1981377319 cites W2001571804 @default.
- W1981377319 cites W2001735713 @default.
- W1981377319 cites W2003864109 @default.
- W1981377319 cites W2004428815 @default.
- W1981377319 cites W2004550803 @default.
- W1981377319 cites W2004693594 @default.
- W1981377319 cites W2005772317 @default.
- W1981377319 cites W2006713735 @default.
- W1981377319 cites W2007349182 @default.
- W1981377319 cites W2009774232 @default.
- W1981377319 cites W2012309329 @default.
- W1981377319 cites W2013102287 @default.
- W1981377319 cites W2013605297 @default.
- W1981377319 cites W2016411515 @default.
- W1981377319 cites W2017356757 @default.
- W1981377319 cites W2020340280 @default.
- W1981377319 cites W2022108138 @default.
- W1981377319 cites W2022890158 @default.
- W1981377319 cites W2026496585 @default.
- W1981377319 cites W2026879435 @default.
- W1981377319 cites W2030548279 @default.
- W1981377319 cites W2031079887 @default.
- W1981377319 cites W2031227547 @default.
- W1981377319 cites W2031972450 @default.
- W1981377319 cites W2032402632 @default.
- W1981377319 cites W2032918317 @default.
- W1981377319 cites W2033279283 @default.
- W1981377319 cites W2036914178 @default.
- W1981377319 cites W2039540766 @default.
- W1981377319 cites W2040215374 @default.
- W1981377319 cites W2040394136 @default.
- W1981377319 cites W2041024803 @default.
- W1981377319 cites W2041982853 @default.
- W1981377319 cites W2042183674 @default.
- W1981377319 cites W2042200677 @default.
- W1981377319 cites W2043620869 @default.
- W1981377319 cites W2046790183 @default.
- W1981377319 cites W2046795038 @default.
- W1981377319 cites W2053379890 @default.
- W1981377319 cites W2053900971 @default.
- W1981377319 cites W2056993732 @default.
- W1981377319 cites W2057162464 @default.