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- W1981400664 abstract "The increasingly stringent requirements laid down by regulatory authorities have brought to an end the largely empirical design of vaccines. Vaccines must now be designed rationally, in order that appropriate immune responses are elicited with few or no side effects. The DC plays a pivotal role in determining the type of immune response that ensues following exposure of the host to an Ag. In this review, we identify some of the features and properties of DCs, and how these properties can be exploited in the design of smart vaccines. The increasingly stringent requirements laid down by regulatory authorities have brought to an end the largely empirical design of vaccines. Vaccines must now be designed rationally, in order that appropriate immune responses are elicited with few or no side effects. The DC plays a pivotal role in determining the type of immune response that ensues following exposure of the host to an Ag. In this review, we identify some of the features and properties of DCs, and how these properties can be exploited in the design of smart vaccines." @default.
- W1981400664 created "2016-06-24" @default.
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- W1981400664 date "2004-04-01" @default.
- W1981400664 modified "2023-10-18" @default.
- W1981400664 title "DCs as targets for vaccine design" @default.
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- W1981400664 doi "https://doi.org/10.1080/14653240410005276" @default.
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