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- W1981420152 abstract "To determine ocular optical parameters that affect axial length elongation in myopic children undergoing overnight orthokeratology.Prospective, noncomparative study.Fifty-nine subjects who met the inclusion criteria were enrolled in this study.Axial length and ocular wavefront aberration were assessed before and 1 year after the start of orthokeratology. Corneal topography was performed, and then corneal multifocality was calculated for a 4-mm pupil. After evaluating simple correlations between axial elongation and optical parameters, multiple linear regression analysis was performed to identify explanatory variables with a statistically significant contribution to axial elongation.Axial length and ocular wavefront aberration before and 1 year after the start of orthokeratology.Fifty-five subjects completed the 1-year follow-up examinations. At baseline, their age ranged from 7.2 to 12.0 years. The manifest spherical equivalent refractive error ranged from -3.50 to -0.75 diopters. The mean axial length significantly increased from 24.20 mm at baseline to 24.43 mm 1 year after treatment. The axial elongation showed significant simple correlations with the change in C2(0), change in second-order aberration, change in coma-like aberration, change in spherical-like aberration, change in total higher-order aberrations, change in corneal multifocality, baseline age, and baseline spherical equivalent refractive error, but not C4(0). Multiple linear regression analysis showed that the change in coma-like aberration was the most relevant variable.Asymmetric corneal shapes, rather than concentric and radially symmetric shapes, have a considerable effect on retardation of axial elongation, suggesting that the inhibitory effect of orthokeratology on myopia progression is caused by mechanisms other than the reduction in peripheral hyperopic defocus." @default.
- W1981420152 created "2016-06-24" @default.
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- W1981420152 date "2015-01-01" @default.
- W1981420152 modified "2023-09-30" @default.
- W1981420152 title "Influence of Ocular Wavefront Aberrations on Axial Length Elongation in Myopic Children Treated with Overnight Orthokeratology" @default.
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- W1981420152 doi "https://doi.org/10.1016/j.ophtha.2014.07.042" @default.
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