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- W1981421324 abstract "With respect to the article by Chirikos et al (May 2002) 1 Chirikos T Hazelton T Tockman M et al. Screening for lung cancer with CT: a preliminary cost-effectiveness analysis. Chest. 2002; : 1507-1514 Abstract Full Text Full Text PDF PubMed Scopus (64) Google Scholar and the accompanying editorial by Dr. Grannis (May 2002), 2 Grannis FW Lung cancer screening: who will pick up the tab?. Chest. 2002; 121: 1388-1390 Abstract Full Text Full Text PDF PubMed Scopus (6) Google Scholar while the analyses and comments are elegant, they do not address the key issue in the lung cancer screening debate. As noted by Dr. Chirikos, “First and foremost, a cost-effective analysis must assume that effectiveness exists.” Dr. Grannis assumes “a very real possibility that LC [lung cancer] screening, despite high initial cost, can save money as well as lives.” It is problematic that these assumptions are unproven and that considerable data are currently available that, at the very least, suggest that the assumptions are incorrect. Lung Cancer Screening DebateCHESTVol. 123Issue 2PreviewIn a very sophisticated analysis (May 2002), Chirikos and colleagues1 report that lung cancer screening with low-radiation-dose CT is likely to be cost-effective if it proves to be effective in reducing lung cancer mortality rates. While the authors’ assumptions regarding costs may be conservative, their assumptions regarding effectiveness are very optimistic. It is important to note that, as the incremental benefits of an intervention approach zero, the incremental cost-effectiveness ratio approaches infinity. Full-Text PDF Lung Cancer Screening DebateCHESTVol. 123Issue 2PreviewWe are grateful to Drs. Gould, Blum, and Rinne for their interest in our article1 and for their thoughtful comments. Full-Text PDF" @default.
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- W1981421324 date "2003-02-01" @default.
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- W1981421324 title "Lung Cancer Screening Debate" @default.
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- W1981421324 doi "https://doi.org/10.1016/s0012-3692(15)32490-9" @default.
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