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- W1981432835 abstract "The teratogenic effects in mice of Colorado tick fever. (CTF) virus, a human pathogen, were demonstrated. Various routes of inoculation, gestational periods, and dosages of virus were studied. The incidence of stillbirth and neonatal death increased significantly after inoculation of pregnant mice with CTF virus. CTF virus crossed the placenta and replicated to high titers in the placental and fetal tissues. Mice that survived the first six weeks of life had neutralizing antibody to CTP virus. Neutralization tests, in which pregnant mice were inoculated with both CTP virus and specific antiserum to CTP virus, validated the teratogenic effects of CTP virus in mice." @default.
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- W1981432835 date "1975-04-01" @default.
- W1981432835 modified "2023-09-27" @default.
- W1981432835 title "Teratogenic Effects of Colorado Tick Fever Virus in Mice" @default.
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- W1981432835 doi "https://doi.org/10.1093/infdis/131.4.397" @default.
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