Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981441330> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1981441330 endingPage "198" @default.
- W1981441330 startingPage "194" @default.
- W1981441330 abstract "Twenty-five cases of fibrous papule of the nose were studied by light microscopy and by immunohistochemistry using a panel of 4 cell markers. These included polyclonal antibodies against S100 protein and Factor XIII-a (FXIII-a), and 2 monoclonal antibodies, MAC 387 which labels monocyte derived macrophage cells and Ulex Europaeus Agglutinin-1 (UEA-1) a pan endothelial cell marker. An increase in the number of S100 protein positive cells, particularly in the upper dermis, was observed in 3 lesions. Melanin was identified in phagocytes in the superficial dermis in 6 lesions, including those with S100 protein positive cells. In all of the papules there was a marked increase in FXIII-a labelling of dendritic connective tissue cells, including spindle, stellate and multinucleate stellate cells. Immunoreactivity with FXIII-a was especially strong in the increased mononuclear dendritic cell population (greater than 80%) seen in the mid- and upper dermis. However, only 15% of the larger multinucleate stellate cells were immunostained with FXIII-a. The results achieved with markers to the macrophage cell series (MAC 387) or endothelial cells (UEA-1) showed no significant increase in labelling of the dermal cell population compared to normal skin taken from the nose. Our study suggests that fibrous papule of the nose, a lesion of uncertain histogenesis, probably represents a proliferative reactive process consisting mainly of dermal dendritic cells as identified by FXIII-a in most of the lesions. There is some evidence that a small percentage of the dendritic cells may represent involuted naevi and be of melanocytic origin." @default.
- W1981441330 created "2016-06-24" @default.
- W1981441330 creator A5033295884 @default.
- W1981441330 creator A5042929940 @default.
- W1981441330 creator A5070028775 @default.
- W1981441330 creator A5089356448 @default.
- W1981441330 date "1989-08-01" @default.
- W1981441330 modified "2023-09-25" @default.
- W1981441330 title "An immunohistochemical study of fibrous papule of the nose: 25 cases" @default.
- W1981441330 cites W1965151036 @default.
- W1981441330 cites W1979320720 @default.
- W1981441330 cites W1980733938 @default.
- W1981441330 cites W1986045811 @default.
- W1981441330 cites W2022669129 @default.
- W1981441330 cites W2038472306 @default.
- W1981441330 cites W2043223572 @default.
- W1981441330 cites W2052067390 @default.
- W1981441330 cites W2055960528 @default.
- W1981441330 cites W2081844098 @default.
- W1981441330 cites W2110447511 @default.
- W1981441330 cites W2321092550 @default.
- W1981441330 doi "https://doi.org/10.1111/j.1600-0560.1989.tb00039.x" @default.
- W1981441330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2571624" @default.
- W1981441330 hasPublicationYear "1989" @default.
- W1981441330 type Work @default.
- W1981441330 sameAs 1981441330 @default.
- W1981441330 citedByCount "34" @default.
- W1981441330 countsByYear W19814413302012 @default.
- W1981441330 countsByYear W19814413302013 @default.
- W1981441330 countsByYear W19814413302015 @default.
- W1981441330 countsByYear W19814413302018 @default.
- W1981441330 countsByYear W19814413302021 @default.
- W1981441330 crossrefType "journal-article" @default.
- W1981441330 hasAuthorship W1981441330A5033295884 @default.
- W1981441330 hasAuthorship W1981441330A5042929940 @default.
- W1981441330 hasAuthorship W1981441330A5070028775 @default.
- W1981441330 hasAuthorship W1981441330A5089356448 @default.
- W1981441330 hasConcept C10205521 @default.
- W1981441330 hasConcept C142724271 @default.
- W1981441330 hasConcept C147483822 @default.
- W1981441330 hasConcept C176891718 @default.
- W1981441330 hasConcept C203014093 @default.
- W1981441330 hasConcept C204232928 @default.
- W1981441330 hasConcept C2777624698 @default.
- W1981441330 hasConcept C2778170410 @default.
- W1981441330 hasConcept C2780851604 @default.
- W1981441330 hasConcept C28328180 @default.
- W1981441330 hasConcept C2908647359 @default.
- W1981441330 hasConcept C71924100 @default.
- W1981441330 hasConcept C86803240 @default.
- W1981441330 hasConcept C95444343 @default.
- W1981441330 hasConcept C99454951 @default.
- W1981441330 hasConceptScore W1981441330C10205521 @default.
- W1981441330 hasConceptScore W1981441330C142724271 @default.
- W1981441330 hasConceptScore W1981441330C147483822 @default.
- W1981441330 hasConceptScore W1981441330C176891718 @default.
- W1981441330 hasConceptScore W1981441330C203014093 @default.
- W1981441330 hasConceptScore W1981441330C204232928 @default.
- W1981441330 hasConceptScore W1981441330C2777624698 @default.
- W1981441330 hasConceptScore W1981441330C2778170410 @default.
- W1981441330 hasConceptScore W1981441330C2780851604 @default.
- W1981441330 hasConceptScore W1981441330C28328180 @default.
- W1981441330 hasConceptScore W1981441330C2908647359 @default.
- W1981441330 hasConceptScore W1981441330C71924100 @default.
- W1981441330 hasConceptScore W1981441330C86803240 @default.
- W1981441330 hasConceptScore W1981441330C95444343 @default.
- W1981441330 hasConceptScore W1981441330C99454951 @default.
- W1981441330 hasIssue "4" @default.
- W1981441330 hasLocation W19814413301 @default.
- W1981441330 hasLocation W19814413302 @default.
- W1981441330 hasOpenAccess W1981441330 @default.
- W1981441330 hasPrimaryLocation W19814413301 @default.
- W1981441330 hasRelatedWork W1877167627 @default.
- W1981441330 hasRelatedWork W1977567269 @default.
- W1981441330 hasRelatedWork W2003557893 @default.
- W1981441330 hasRelatedWork W2013745628 @default.
- W1981441330 hasRelatedWork W2042184740 @default.
- W1981441330 hasRelatedWork W2168580299 @default.
- W1981441330 hasRelatedWork W4212877682 @default.
- W1981441330 hasRelatedWork W4243272244 @default.
- W1981441330 hasRelatedWork W4312460065 @default.
- W1981441330 hasRelatedWork W4313517774 @default.
- W1981441330 hasVolume "16" @default.
- W1981441330 isParatext "false" @default.
- W1981441330 isRetracted "false" @default.
- W1981441330 magId "1981441330" @default.
- W1981441330 workType "article" @default.