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• W1981448997 abstract "Annals of the New York Academy of SciencesVolume 273, Issue 1 p. 159-166 ALCOHOL AS A EUPHORIANT DRUG: SEARCHING FOR A NEUROCHEMICAL BASIS* John A. Ewing, John A. Ewing Center for Alcohol Studies and Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514Search for more papers by this authorBeatrice A. Rouse, Beatrice A. Rouse Center for Alcohol Studies and Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514Search for more papers by this authorRobert A. Mueller, Robert A. Mueller Department of Anesthesiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514Search for more papers by this authorKenneth C. Mills, Kenneth C. Mills Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514Search for more papers by this author John A. Ewing, John A. Ewing Center for Alcohol Studies and Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514Search for more papers by this authorBeatrice A. Rouse, Beatrice A. Rouse Center for Alcohol Studies and Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514Search for more papers by this authorRobert A. Mueller, Robert A. Mueller Department of Anesthesiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514Search for more papers by this authorKenneth C. Mills, Kenneth C. Mills Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514Search for more papers by this author First published: May 1976 https://doi.org/10.1111/j.1749-6632.1976.tb52878.xCitations: 12 * Supported in part by a North Carolina State appropriation to the Center for Alcohol Studies, by a grant from Ayerst Laboratories (J.A.E.), by United States Public Health Service Grant GM19088, and by North Carolina Alcoholism Research Authority Grant 7406 (R.A.M.). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Wallgren, H. & H. Barry. 1970. Actions of Alcohol. American Elsevier Publishing Co. Inc. New York, N.Y. . 2 Masserman, J. H. 1943. Behavior and Neurosis. University of Chicago Press. Chicago , Ill. . 3 Walsh, M. J., E. B. Truitt & V. E. Davis. 1970. Acetaldehyde mediation in the mechanism of ethanol induced changes in norepinephrine metabolism. Mol. Pharmacol. 6: 416– 424. 4 Holtzman, S. G. & F. H. Schneider. 1974. Comparison of acetaldehyde and ethanol depression of motor activity in mice. Life Sci. 14: 1243– 1250. 5 Redmond, G. P. & G. Cohen. 1972. Sex differences in acetaldehyde exhalation following ethanol administration in C57BL mice.. Nature (London) 236: 117– 119. 6 Truitt, E. B.Jr., 1971. Blood acetaldehyde levels after alcohol consumption by alcoholic and non-alcoholic subjects. In Biological Aspects of Alcohol. M. K. Roach, W. M. McIsaac & P. J. Creaven, Eds. : 212– 232. University of Texas Press Austin , Texas . 7 Majchrowicz, E. & J. H. Mendelson. 1972. Blood concentration of acetaldehyde and ethanol in chronic alcoholics.. Science 168: 1100– 1102. 8 Korsten, M. A., S. Matsuzaki, L. Feinman & C. S. Lieber. 1975. High blood acetaldehyde levels after ethanol administration: difference between alcoholic and nonalcoholic subjects.. N. Engl. J. Med. 292: 386– 389. 9 Ewing, J. A., B. A. Rouse & E. D. Pellizzari. 1974. Alcohol sensitivity and ethnic background.. Amer. J. Psychiat. 131: 206– 210. 10 Williams, A. F. 1966. Social drinking, anxiety and depression. J. Personal. Soc. Psychol. 3: 689– 693. 11 Tamerin, J. S. & J. H. Mendelson. 1969. The psychodynamics of chronic inebriation.. Amer. J. Psychiat. 125: 886– 899. 12 Nemiah, J. C. 1967. Obsessive-compulsive reaction. In Comprehensive Textbook of Psychiatry. A. M. Freedman & H. I. Kaplan, Eds. : 912– 928. The Williams & Wilkins Co. Baltimore , Md. 13 Mcclelland, D. C, W. N. Davis, R. Kalin & E. Wanner. 1972. The Drinking Man. The Free Press New York, N.Y. 14 Anton, A. H. 1965. Ethanol and urinary catecholamines in man. Clin. Pharmacol. Ther. 6: 462– 469. 15 Brodie, B. B., S. Spector & P. A. Shore. 1959. Interaction of drugs with norepinephrine in the brain.. Pharmacol. Rev. 11: 548– 564. 16 Carlsson, A., J. Engel & T. Svensson. 1972. Inhibition of ethanol-induced excitation in mice and rats by a-methyl-p-tyrosine. Psychopharmacologia 26: 307– 312. 17 Myers, R. D. & W. R. Veale. 1968. Alcohol preference in the rat.. Science 160: 1469– 1471. 18 Ogata, M., J. H. Mendelson, N. K. Mello & E. Majchrowicz. 1971. Ad renal function and alcoholism.. Psychosom. Med. 33: 159– 180. 19 Hunt, W. A. & E. Majchrowicz. 1974. Alterations in the turnover of brain norepinephrine and dopamine in alcohol-dependent rats.. J. Neurochem. 23: 549– 552. 20 Ijiri, I. 1974. Studies on the relationship between the concentrations of blood acetaldehyde and urinary catecholamine and the symptoms after drinking alcohol. Jap. J. Studies Alc. 9: 35– 59. 21 Lahti, R. A. & E. Majchrowicz. 1974. Ethanol and acetaldehyde effects on metabolism and binding of biogenic amines.. Quart. J. Studies Alc. 35: 1– 14. 22 Ahlenius, S., A. Carlsson, J. Engel, H. Svensson & P. Sodersten. 1973. Antagonism by alphamethyltyrosine of the ethanol-induced stimulation and euphoria in man.. Clin. Pharmacol. Ther. 14: 586– 591. 23 Geffen, L. 1974. Dopamineβ-hydroxylase as an index of sympathetic function. Life Sci. 14: 1593– 1604. 24 Ewing, J. A., B. A. Rouse. & R. A. Mueller. 1974. Alcohol susceptibility and plasma dopamine β-hydroxylase activity.. Res. Commun. Chem. Pathol. Pharmacol. 8: 551– 554. 25 Aitken, R. C. B. & A. K. Zeally. 1970. Measurement of mood.. Brit. J. Hosp. Med. 4: 215– 224. 26 Little, J. C. & N. I. McPhail. 1973. Measures of depressive mood at monthly intervals.. Brit. J. Psychiat. 122: 447– 452. 27 Bond, A. & M. Lader. 1974. The use of analogue scales in rating subjective feelings.. Brit. J. Med. Psychol. 47: 211– 218. 28 Ewing, J. A., B. A. Rouse, R. A. Mueller & K. C. Mills. 1975. Dopamine β-hydroxylase activity as a predictor of response to alcohol.. Jap. J. Studies Alc. 10: 61– 69. 29 Kline, N. S., J. C. Wren, T. B. Cooper, E. Varger & O. Canal. 1974. Evaluation of lithium therapy in chronic and periodic alcoholism.. Amer. J. Med. Sci. 268: 15– 22. 30 Dent, J. Y. 1934. Apomorphine in the treatment of anxiety states with special reference to alcoholism. Brit. J. Inebriety 32: 65– 88. 31 Schlatter, E. K. E. & S. Lal. 1972. Treatment of alcoholism with Dent's oral apomorphine method. Quart. J. Studies Alc. 33: 430– 436. 32 Carlsson, A., J. Engel, U. Strömbom, T. H. Svensson & B. Waldeck. 1974. Suppression by dopaminc-agonists of the ethanol-induced stimulation of locomotor activity and brain dopamine synthesis. Naunyn-Schmiedeberg's Arch. Exp. Pathol. Pharmakol. 283: 117– 128. Citing Literature Volume273, Issue1Work in Progress on AlcoholismMay 1976Pages 159-166 ReferencesRelatedInformation" @default.
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