FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981454564> ?p ?o ?g. }

• W1981454564 endingPage "1000" @default.
• W1981454564 startingPage "1000" @default.
• W1981454564 abstract "Although the link between epidermal lamellar body lipids and stratum corneum barrier function is well established, a role for lamellar body lipids in desquamation remains unproved. We examined skin biopsy material from three family members of a Palestinian kindred with a multisystem disorder of altered lipid metabolism, ichthyosis, and deposition of fat droplets in multiple tissues (Chanarin-Dorfman syndrome, neutral lipid storage disease). Thin-section and freeze-fracture ultrastructural studies revealed a distinctive lamellar body abnormality: multilaminated spherules that distorted and displaced the normal internal disk structure of these organelles. Whereas these spherules remained interspersed with secreted lamellar body contents within the intercellular spaces of the outer epidermis, at the stratum granulosum-stratum corneum interface they apparently dispersed into electron-lucent slits. These studies therefore provide strong support for the concept that lamellar body-derived lipids influence stratum corneum desquamation and further suggest that abnormalities of neutral lipid-alkane metabolism influence normal epidermal shedding." @default.
• W1981454564 created "2016-06-24" @default.
• W1981454564 creator A5050608918 @default.
• W1981454564 date "1985-08-01" @default.
• W1981454564 modified "2023-10-18" @default.
• W1981454564 title "Neutral Lipid Storage Disease With Ichthyosis" @default.
• W1981454564 cites W1970943613 @default.
• W1981454564 cites W1975986537 @default.
• W1981454564 cites W1995713977 @default.
• W1981454564 cites W1997181136 @default.
• W1981454564 cites W2009568845 @default.
• W1981454564 cites W2012478400 @default.
• W1981454564 cites W2016964864 @default.
• W1981454564 cites W2027455626 @default.
• W1981454564 cites W2027482987 @default.
• W1981454564 cites W2035660063 @default.
• W1981454564 cites W2040570209 @default.
• W1981454564 cites W2053138332 @default.
• W1981454564 cites W2062521250 @default.
• W1981454564 cites W2077884934 @default.
• W1981454564 cites W2083263272 @default.
• W1981454564 cites W2086001407 @default.
• W1981454564 cites W2101369093 @default.
• W1981454564 cites W2102742421 @default.
• W1981454564 cites W2110496617 @default.
• W1981454564 cites W2111211507 @default.
• W1981454564 cites W2169484065 @default.
• W1981454564 cites W2284476116 @default.
• W1981454564 cites W2413287599 @default.
• W1981454564 doi "https://doi.org/10.1001/archderm.1985.01660080054014" @default.
• W1981454564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4026335" @default.
• W1981454564 hasPublicationYear "1985" @default.
• W1981454564 type Work @default.
• W1981454564 sameAs 1981454564 @default.
• W1981454564 citedByCount "70" @default.
• W1981454564 countsByYear W19814545642012 @default.
• W1981454564 countsByYear W19814545642014 @default.
• W1981454564 countsByYear W19814545642015 @default.
• W1981454564 countsByYear W19814545642016 @default.
• W1981454564 countsByYear W19814545642018 @default.
• W1981454564 countsByYear W19814545642019 @default.
• W1981454564 countsByYear W19814545642023 @default.
• W1981454564 crossrefType "journal-article" @default.
• W1981454564 hasAuthorship W1981454564A5050608918 @default.
• W1981454564 hasConcept C105702510 @default.
• W1981454564 hasConcept C142724271 @default.
• W1981454564 hasConcept C145156650 @default.
• W1981454564 hasConcept C16005928 @default.
• W1981454564 hasConcept C179927520 @default.
• W1981454564 hasConcept C185592680 @default.
• W1981454564 hasConcept C25095133 @default.
• W1981454564 hasConcept C2776003677 @default.
• W1981454564 hasConcept C2776292323 @default.
• W1981454564 hasConcept C2776458125 @default.
• W1981454564 hasConcept C2778370115 @default.
• W1981454564 hasConcept C2779483664 @default.
• W1981454564 hasConcept C2779922919 @default.
• W1981454564 hasConcept C4733338 @default.
• W1981454564 hasConcept C55493867 @default.
• W1981454564 hasConcept C71924100 @default.
• W1981454564 hasConcept C77851909 @default.
• W1981454564 hasConcept C8010536 @default.
• W1981454564 hasConcept C81241287 @default.
• W1981454564 hasConcept C86803240 @default.
• W1981454564 hasConcept C87555872 @default.
• W1981454564 hasConcept C95444343 @default.
• W1981454564 hasConceptScore W1981454564C105702510 @default.
• W1981454564 hasConceptScore W1981454564C142724271 @default.
• W1981454564 hasConceptScore W1981454564C145156650 @default.
• W1981454564 hasConceptScore W1981454564C16005928 @default.
• W1981454564 hasConceptScore W1981454564C179927520 @default.
• W1981454564 hasConceptScore W1981454564C185592680 @default.
• W1981454564 hasConceptScore W1981454564C25095133 @default.
• W1981454564 hasConceptScore W1981454564C2776003677 @default.
• W1981454564 hasConceptScore W1981454564C2776292323 @default.
• W1981454564 hasConceptScore W1981454564C2776458125 @default.
• W1981454564 hasConceptScore W1981454564C2778370115 @default.
• W1981454564 hasConceptScore W1981454564C2779483664 @default.
• W1981454564 hasConceptScore W1981454564C2779922919 @default.
• W1981454564 hasConceptScore W1981454564C4733338 @default.
• W1981454564 hasConceptScore W1981454564C55493867 @default.
• W1981454564 hasConceptScore W1981454564C71924100 @default.
• W1981454564 hasConceptScore W1981454564C77851909 @default.
• W1981454564 hasConceptScore W1981454564C8010536 @default.
• W1981454564 hasConceptScore W1981454564C81241287 @default.
• W1981454564 hasConceptScore W1981454564C86803240 @default.
• W1981454564 hasConceptScore W1981454564C87555872 @default.
• W1981454564 hasConceptScore W1981454564C95444343 @default.
• W1981454564 hasIssue "8" @default.
• W1981454564 hasLocation W19814545641 @default.
• W1981454564 hasLocation W19814545642 @default.
• W1981454564 hasOpenAccess W1981454564 @default.
• W1981454564 hasPrimaryLocation W19814545641 @default.
• W1981454564 hasRelatedWork W1576934053 @default.
• W1981454564 hasRelatedWork W1980928141 @default.
• W1981454564 hasRelatedWork W1981454564 @default.
• W1981454564 hasRelatedWork W2001795926 @default.
• W1981454564 hasRelatedWork W200843782 @default.

• next