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- W1981503162 abstract "Sterol hydroperoxides 3β-hydroxy-5α-cholest-6-ene-hydroperoxide and 3β-hydroxycholest-5-ene-7α-hydroperoxide show weak dose-response direct mutagenicity towards Salmonella typhimurium strain TA1537 in a liquid medium incubation bioassay. Responses were compromised by metabolism of the sterol hydroperoxides and by phase separation during the incubation period. Mutagenicity responses were increased by added superoxide dismutase but diminished by added rat liver S9 enzymes and abolished by added catalase. Catalase also abolished the stimulatory effect of superoxide dismutase. These results indicate that superoxide and peroxide be implicated in the mutagenicity responses." @default.
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- W1981503162 date "1986-06-01" @default.
- W1981503162 modified "2023-10-17" @default.
- W1981503162 title "Mutagenic sterol hydroperoxides" @default.
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- W1981503162 doi "https://doi.org/10.1016/0027-5107(86)90098-9" @default.
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