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- W1981625466 abstract "This report calls attention to an unappreciated cause of both acute and chronic aortic regurgitation (AR). Although stenosis develops in most patients with a congenitally bicuspid aortic valve (BAV), in others with this anomaly, pure AR (no element of stenosis) develops, some in the absence of infection or other clear etiology. We describe 5 men who underwent aortic valve replacement for pure AR associated with a BAV containing an anomalous cord attaching the raphe of the conjoined cusp near its free margin to the wall of the ascending aorta cephalad to the sinotubular junction. Three of these 5 patients had a history of progressive dyspnea, and the anomalous cord, which was intact at operation, appeared to cause chronic AR by preventing proper coaptation of the 2 aortic valve cusps. The other 2 patients heard a “pop” during physical exertion and immediately became dyspneic, and at operation, the anomalous cord was found to have ruptured. Prolapse of the conjoined aortic valve cusp toward the left ventricular cavity resulted in severe acute AR. This variant of the purely regurgitant BAV may cause either chronic AR (when the anomalous cord does not rupture) or acute severe AR (when the cord ruptures)." @default.
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- W1981625466 date "2014-01-01" @default.
- W1981625466 modified "2023-10-18" @default.
- W1981625466 title "Anomalous Cord From the Raphe of a Congenitally Bicuspid Aortic Valve to the Aortic Wall Producing Either Acute or Chronic Aortic Regurgitation" @default.
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- W1981625466 doi "https://doi.org/10.1016/j.jacc.2013.09.030" @default.
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