Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981652024> ?p ?o ?g. }
- W1981652024 endingPage "39" @default.
- W1981652024 startingPage "31" @default.
- W1981652024 abstract "The role of GABA(A) and GABA(B) receptors in the substantia nigra pars reticulata and the globus pallidus in turning behaviour of rats was studied. Unilateral injection of the GABA(A) receptor agonist muscimol (25 and 50 ng) into the substantia nigra pars reticulata elicited contralateral pivoting, namely tight head-to-tail turning marked by abnormal hindlimb backward stepping. This effect was GABA(A) receptor specific, since it was dose-dependent and prevented by co-administration of the GABA(A) receptor antagonist bicuculline (100 and 200 ng) which alone did not elicit turning behaviour. Unilateral injection of the GABA(B) receptor agonist baclofen (100 and 200 ng) into the substantia nigra pars reticulata also produced contralateral pivoting. This effect was GABA(B) receptor specific, since it was dose-dependent and inhibited by the GABA(B) receptor antagonist CGP 55845 (200 ng) which alone did not elicit turning behaviour. In contrast, unilateral injection of bicuculline (100 and 200 ng) into the globus pallidus produced contralateral circling, namely turning marked by normal stepping. This effect was GABA(A) receptor specific, since it was dose-dependent and prevented by muscimol (50 ng), which alone did not elicit turning behaviour. Unilateral injection of baclofen (100 and 200 ng) into the globus pallidus dose-dependently produced ipsilateral pivoting; this effect was inhibited by CGP 55845 (200 ng), which alone did not elicit turning behaviour. The present study demonstrates that GABA(A) and GABA(B) receptors in the globus pallidus and the substantina nigra pars reticulata play differential roles in the production of turning behaviour. This study underlines the notion that the two types of turning, namely pivoting and circling, are valid tools to map out the information flow across the basal ganglia." @default.
- W1981652024 created "2016-06-24" @default.
- W1981652024 creator A5004442540 @default.
- W1981652024 creator A5025226768 @default.
- W1981652024 creator A5034180830 @default.
- W1981652024 creator A5089437734 @default.
- W1981652024 date "2010-04-01" @default.
- W1981652024 modified "2023-10-07" @default.
- W1981652024 title "Differential role of GABAA and GABAB receptors in two distinct output stations of the rat striatum: studies on the substantia nigra pars reticulata and the globus pallidus" @default.
- W1981652024 cites W1485305560 @default.
- W1981652024 cites W1490680688 @default.
- W1981652024 cites W1529379087 @default.
- W1981652024 cites W1575810634 @default.
- W1981652024 cites W1678465678 @default.
- W1981652024 cites W1854209661 @default.
- W1981652024 cites W1965996705 @default.
- W1981652024 cites W1966261503 @default.
- W1981652024 cites W1967838925 @default.
- W1981652024 cites W1969817492 @default.
- W1981652024 cites W1972456289 @default.
- W1981652024 cites W1980396274 @default.
- W1981652024 cites W1982814832 @default.
- W1981652024 cites W1983907708 @default.
- W1981652024 cites W1988253925 @default.
- W1981652024 cites W1992238026 @default.
- W1981652024 cites W1992997151 @default.
- W1981652024 cites W1993328141 @default.
- W1981652024 cites W1994695196 @default.
- W1981652024 cites W1997275694 @default.
- W1981652024 cites W1999961963 @default.
- W1981652024 cites W2013677017 @default.
- W1981652024 cites W2015200019 @default.
- W1981652024 cites W2018379282 @default.
- W1981652024 cites W2020221913 @default.
- W1981652024 cites W2024486693 @default.
- W1981652024 cites W2025323802 @default.
- W1981652024 cites W2025597537 @default.
- W1981652024 cites W2027797974 @default.
- W1981652024 cites W2027873336 @default.
- W1981652024 cites W2029015057 @default.
- W1981652024 cites W2030034288 @default.
- W1981652024 cites W2032830671 @default.
- W1981652024 cites W2034531255 @default.
- W1981652024 cites W2034998625 @default.
- W1981652024 cites W2037421421 @default.
- W1981652024 cites W2039633685 @default.
- W1981652024 cites W2042965047 @default.
- W1981652024 cites W2046437714 @default.
- W1981652024 cites W2050750445 @default.
- W1981652024 cites W2052207845 @default.
- W1981652024 cites W2058727305 @default.
- W1981652024 cites W2062635719 @default.
- W1981652024 cites W2069131425 @default.
- W1981652024 cites W2073618643 @default.
- W1981652024 cites W2075126242 @default.
- W1981652024 cites W2075546748 @default.
- W1981652024 cites W2083123019 @default.
- W1981652024 cites W2083695993 @default.
- W1981652024 cites W2085387776 @default.
- W1981652024 cites W2088287866 @default.
- W1981652024 cites W2090775904 @default.
- W1981652024 cites W2091309518 @default.
- W1981652024 cites W2092659452 @default.
- W1981652024 cites W2104965306 @default.
- W1981652024 cites W2111360128 @default.
- W1981652024 cites W2138008736 @default.
- W1981652024 cites W2139633309 @default.
- W1981652024 cites W2163123219 @default.
- W1981652024 cites W2171622636 @default.
- W1981652024 cites W2313798176 @default.
- W1981652024 cites W2937984256 @default.
- W1981652024 cites W4237569337 @default.
- W1981652024 doi "https://doi.org/10.1016/j.neuroscience.2010.01.054" @default.
- W1981652024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20132872" @default.
- W1981652024 hasPublicationYear "2010" @default.
- W1981652024 type Work @default.
- W1981652024 sameAs 1981652024 @default.
- W1981652024 citedByCount "18" @default.
- W1981652024 countsByYear W19816520242012 @default.
- W1981652024 countsByYear W19816520242013 @default.
- W1981652024 countsByYear W19816520242015 @default.
- W1981652024 countsByYear W19816520242016 @default.
- W1981652024 countsByYear W19816520242018 @default.
- W1981652024 countsByYear W19816520242019 @default.
- W1981652024 countsByYear W19816520242020 @default.
- W1981652024 countsByYear W19816520242023 @default.
- W1981652024 crossrefType "journal-article" @default.
- W1981652024 hasAuthorship W1981652024A5004442540 @default.
- W1981652024 hasAuthorship W1981652024A5025226768 @default.
- W1981652024 hasAuthorship W1981652024A5034180830 @default.
- W1981652024 hasAuthorship W1981652024A5089437734 @default.
- W1981652024 hasConcept C101027131 @default.
- W1981652024 hasConcept C126322002 @default.
- W1981652024 hasConcept C134018914 @default.
- W1981652024 hasConcept C137183658 @default.
- W1981652024 hasConcept C168258287 @default.
- W1981652024 hasConcept C170493617 @default.
- W1981652024 hasConcept C185592680 @default.