FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981670950> ?p ?o ?g. }

• W1981670950 endingPage "259" @default.
• W1981670950 startingPage "252" @default.
• W1981670950 abstract "To achieve a better understanding of taxol metabolism and accumulation in Taxus cell cultures, a T. baccata cell line growing for 20 days in a selected growth medium was treated at the beginning of the experiment with several concentrations of taxol (25, 50, 100 and 200mgL(-1)). Compared with an untreated control, all these taxol concentrations stimulated cell-associated taxol content (up to 32.7 times in the presence of 200mgL(-1) exogenous taxol), although higher concentrations significantly depressed cell viability. DNA laddering analysis revealed that the viability reduction was not related to apoptosis, suggesting that taxol itself was the primary responsible factor. On the basis of RT-PCR expression analysis of genes encoding taxadiene synthase (ts) and 1-deoxy-d-xylulose-5-phosphate synthase (dxs) from treated and nontreated T. baccata cell line cultures, it was observed that exogenous taxol clearly induced the mRNA levels of both taxane-related enzymes. Additionally, we found that exogenous taxol caused a considerable increase in taxadiene synthase activity, although in no case did this coincide with the highest levels of taxol observed at the end of the culture. The effect of exogenous taxol on the content of other related taxanes was also considered." @default.
• W1981670950 created "2016-06-24" @default.
• W1981670950 creator A5027483979 @default.
• W1981670950 creator A5028112907 @default.
• W1981670950 creator A5050284391 @default.
• W1981670950 creator A5051712124 @default.
• W1981670950 creator A5052395692 @default.
• W1981670950 creator A5058161417 @default.
• W1981670950 creator A5073731058 @default.
• W1981670950 creator A5084812532 @default.
• W1981670950 date "2009-04-01" @default.
• W1981670950 modified "2023-10-14" @default.
• W1981670950 title "Effect of taxol feeding on taxol and related taxane production in Taxus baccata suspension cultures" @default.
• W1981670950 cites W104788802 @default.
• W1981670950 cites W133256458 @default.
• W1981670950 cites W1965708712 @default.
• W1981670950 cites W1968563077 @default.
• W1981670950 cites W1978970998 @default.
• W1981670950 cites W1983276169 @default.
• W1981670950 cites W1995027325 @default.
• W1981670950 cites W1998966075 @default.
• W1981670950 cites W2010705160 @default.
• W1981670950 cites W2012616903 @default.
• W1981670950 cites W2014500698 @default.
• W1981670950 cites W2018163896 @default.
• W1981670950 cites W2021295704 @default.
• W1981670950 cites W2026311140 @default.
• W1981670950 cites W2029990071 @default.
• W1981670950 cites W2034985526 @default.
• W1981670950 cites W2040703648 @default.
• W1981670950 cites W2047233093 @default.
• W1981670950 cites W2052086175 @default.
• W1981670950 cites W2057320135 @default.
• W1981670950 cites W2059925042 @default.
• W1981670950 cites W2065762972 @default.
• W1981670950 cites W2077545872 @default.
• W1981670950 cites W2079541078 @default.
• W1981670950 cites W2080916629 @default.
• W1981670950 cites W2082462476 @default.
• W1981670950 cites W2105061879 @default.
• W1981670950 cites W2106346045 @default.
• W1981670950 cites W2119254008 @default.
• W1981670950 cites W2127632782 @default.
• W1981670950 cites W213077667 @default.
• W1981670950 cites W2164200780 @default.
• W1981670950 cites W2167896636 @default.
• W1981670950 cites W2294699865 @default.
• W1981670950 cites W247513487 @default.
• W1981670950 cites W28827870 @default.
• W1981670950 cites W4213080860 @default.
• W1981670950 cites W4293247451 @default.
• W1981670950 cites W71872835 @default.
• W1981670950 doi "https://doi.org/10.1016/j.nbt.2008.11.001" @default.
• W1981670950 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19101660" @default.
• W1981670950 hasPublicationYear "2009" @default.
• W1981670950 type Work @default.
• W1981670950 sameAs 1981670950 @default.
• W1981670950 citedByCount "48" @default.
• W1981670950 countsByYear W19816709502012 @default.
• W1981670950 countsByYear W19816709502013 @default.
• W1981670950 countsByYear W19816709502014 @default.
• W1981670950 countsByYear W19816709502015 @default.
• W1981670950 countsByYear W19816709502016 @default.
• W1981670950 countsByYear W19816709502017 @default.
• W1981670950 countsByYear W19816709502018 @default.
• W1981670950 countsByYear W19816709502019 @default.
• W1981670950 countsByYear W19816709502020 @default.
• W1981670950 countsByYear W19816709502021 @default.
• W1981670950 countsByYear W19816709502022 @default.
• W1981670950 countsByYear W19816709502023 @default.
• W1981670950 crossrefType "journal-article" @default.
• W1981670950 hasAuthorship W1981670950A5027483979 @default.
• W1981670950 hasAuthorship W1981670950A5028112907 @default.
• W1981670950 hasAuthorship W1981670950A5050284391 @default.
• W1981670950 hasAuthorship W1981670950A5051712124 @default.
• W1981670950 hasAuthorship W1981670950A5052395692 @default.
• W1981670950 hasAuthorship W1981670950A5058161417 @default.
• W1981670950 hasAuthorship W1981670950A5073731058 @default.
• W1981670950 hasAuthorship W1981670950A5084812532 @default.
• W1981670950 hasConcept C121608353 @default.
• W1981670950 hasConcept C181199279 @default.
• W1981670950 hasConcept C185592680 @default.
• W1981670950 hasConcept C190283241 @default.
• W1981670950 hasConcept C2777292972 @default.
• W1981670950 hasConcept C2777511904 @default.
• W1981670950 hasConcept C2778894183 @default.
• W1981670950 hasConcept C530470458 @default.
• W1981670950 hasConcept C53227056 @default.
• W1981670950 hasConcept C54355233 @default.
• W1981670950 hasConcept C55493867 @default.
• W1981670950 hasConcept C59822182 @default.
• W1981670950 hasConcept C62112901 @default.
• W1981670950 hasConcept C81885089 @default.
• W1981670950 hasConcept C86803240 @default.
• W1981670950 hasConceptScore W1981670950C121608353 @default.
• W1981670950 hasConceptScore W1981670950C181199279 @default.
• W1981670950 hasConceptScore W1981670950C185592680 @default.
• W1981670950 hasConceptScore W1981670950C190283241 @default.

• next