FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981699237> ?p ?o ?g. }

• W1981699237 endingPage "67" @default.
• W1981699237 startingPage "67" @default.
• W1981699237 abstract "Helicobacter canadensis is an emerging human pathogen and zoonotic agent. The genome of H. canadensis was sequenced previously and determined to contain 29 annotated coding regions associated with homopolymeric tracts.Twenty-one of the repeat-associated coding regions were determined to be potentially transcriptionally or translationally phase variable. In each case the homopolymeric tract was within the predicted promoter region or at the 5' end of the coding region, respectively. However, eight coding sequences were identified with simple sequence repeats toward the 3' end of the open reading frame. In these cases, the repeat tract would be too far into the coding region to be mediating translational phase variation. All of the 29 coding region-associated homopolymeric tracts display variability in tract length in the sequencing read data.Twenty-nine coding regions have been identified in the genome sequence of Helicobacter canadensis strain NCTC13241 that show variations in homopolymeric tract length in the bacterial population, indicative of phase variation. Five of these are potentially associated with promoter regions, which would lead to transcriptional phase variation. Translational phase variation usually switches expression of a gene ON and OFF due to the repeat region being located sufficiently close to the initiation codon for the resulting frame-shift to lead to a premature termination codon and stop the translation of the protein. Sixteen of the 29 coding regions have homopolymeric tracts characteristic of translational phase variation. For eight coding sequences with repeats located later in the reading frame, changes in the repeat tract length would alter the protein sequence at the C-terminus but not stop the expression of the protein. This mechanism of C-terminal phase variation has implications for stochastic switching of protein sequence in bacterial species that already undergo transcriptional and translational phase variation." @default.
• W1981699237 created "2016-06-24" @default.
• W1981699237 creator A5017196239 @default.
• W1981699237 creator A5023116254 @default.
• W1981699237 creator A5050397336 @default.
• W1981699237 creator A5051916129 @default.
• W1981699237 creator A5052546138 @default.
• W1981699237 creator A5067887088 @default.
• W1981699237 creator A5079219438 @default.
• W1981699237 date "2010-01-01" @default.
• W1981699237 modified "2023-10-16" @default.
• W1981699237 title "Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching" @default.
• W1981699237 cites W118969886 @default.
• W1981699237 cites W1576217642 @default.
• W1981699237 cites W1965127354 @default.
• W1981699237 cites W1981141854 @default.
• W1981699237 cites W1985336031 @default.
• W1981699237 cites W1987835960 @default.
• W1981699237 cites W1992600280 @default.
• W1981699237 cites W1993023516 @default.
• W1981699237 cites W1998642520 @default.
• W1981699237 cites W2004898424 @default.
• W1981699237 cites W2013468149 @default.
• W1981699237 cites W2014484567 @default.
• W1981699237 cites W2016299826 @default.
• W1981699237 cites W2033457917 @default.
• W1981699237 cites W2035791573 @default.
• W1981699237 cites W2045060315 @default.
• W1981699237 cites W2047265762 @default.
• W1981699237 cites W2048005365 @default.
• W1981699237 cites W2058322671 @default.
• W1981699237 cites W2066453505 @default.
• W1981699237 cites W2084807013 @default.
• W1981699237 cites W2093692587 @default.
• W1981699237 cites W2099604214 @default.
• W1981699237 cites W2103347050 @default.
• W1981699237 cites W2110132014 @default.
• W1981699237 cites W2112814753 @default.
• W1981699237 cites W2114774210 @default.
• W1981699237 cites W2119403138 @default.
• W1981699237 cites W2128730778 @default.
• W1981699237 cites W2130904301 @default.
• W1981699237 cites W2134489112 @default.
• W1981699237 cites W2143107875 @default.
• W1981699237 cites W2143626786 @default.
• W1981699237 cites W2144178003 @default.
• W1981699237 cites W2150192620 @default.
• W1981699237 cites W2157931451 @default.
• W1981699237 cites W2161631631 @default.
• W1981699237 cites W2164926676 @default.
• W1981699237 cites W2168671553 @default.
• W1981699237 cites W2170876859 @default.
• W1981699237 cites W2417892265 @default.
• W1981699237 cites W2424052232 @default.
• W1981699237 cites W25206051 @default.
• W1981699237 doi "https://doi.org/10.1186/1471-2164-11-67" @default.
• W1981699237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2823697" @default.
• W1981699237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20105305" @default.
• W1981699237 hasPublicationYear "2010" @default.
• W1981699237 type Work @default.
• W1981699237 sameAs 1981699237 @default.
• W1981699237 citedByCount "15" @default.
• W1981699237 countsByYear W19816992372012 @default.
• W1981699237 countsByYear W19816992372014 @default.
• W1981699237 countsByYear W19816992372015 @default.
• W1981699237 countsByYear W19816992372016 @default.
• W1981699237 countsByYear W19816992372017 @default.
• W1981699237 countsByYear W19816992372020 @default.
• W1981699237 countsByYear W19816992372022 @default.
• W1981699237 countsByYear W19816992372023 @default.
• W1981699237 crossrefType "journal-article" @default.
• W1981699237 hasAuthorship W1981699237A5017196239 @default.
• W1981699237 hasAuthorship W1981699237A5023116254 @default.
• W1981699237 hasAuthorship W1981699237A5050397336 @default.
• W1981699237 hasAuthorship W1981699237A5051916129 @default.
• W1981699237 hasAuthorship W1981699237A5052546138 @default.
• W1981699237 hasAuthorship W1981699237A5067887088 @default.
• W1981699237 hasAuthorship W1981699237A5079219438 @default.
• W1981699237 hasBestOaLocation W19816992371 @default.
• W1981699237 hasConcept C104317684 @default.
• W1981699237 hasConcept C105580179 @default.
• W1981699237 hasConcept C127716648 @default.
• W1981699237 hasConcept C141231307 @default.
• W1981699237 hasConcept C144024400 @default.
• W1981699237 hasConcept C149923435 @default.
• W1981699237 hasConcept C167625842 @default.
• W1981699237 hasConcept C176990463 @default.
• W1981699237 hasConcept C179069550 @default.
• W1981699237 hasConcept C20580545 @default.
• W1981699237 hasConcept C2908647359 @default.
• W1981699237 hasConcept C29511175 @default.
• W1981699237 hasConcept C47289529 @default.
• W1981699237 hasConcept C54355233 @default.
• W1981699237 hasConcept C86803240 @default.
• W1981699237 hasConcept C91779695 @default.
• W1981699237 hasConceptScore W1981699237C104317684 @default.
• W1981699237 hasConceptScore W1981699237C105580179 @default.
• W1981699237 hasConceptScore W1981699237C127716648 @default.

• next