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- W1981799503 abstract "Gelatin hydrogels cross-linked by y-ray irradiation using 60Co as gamma-ray source were prepared. As a model of controlled release of low-molecular-weight compounds, absorption and release of methylene blue, a water-soluble cationic dye, was investigated. Irradiated gelatin hydrogels did not redissolve at temperatures over 40 degrees C, while unirradiated gels were thermoplastic and reversibly changed the stage between gel and sol. Measurement of both the wet weight after swelling in distilled water and dry weight after freeze-drying showed that the higher-dose irradiation gave stiffer and more compact gels with the lower specific water content, irrespective of the absorbed dose rate. The time-course of absorption and release of methylene blue in aqueous solution was measured. Since absorption of dye into gelatin gels was much affected by liquid phase pH, amount of absorption was higher in pH above an IEP of gelatins. Moreover, the absorption and release of methylene blue with Type-B gelatin were higher than with Type-A gelatin, respectively. Therefore, absorption and release of the dye depend on the electrostatic interaction between the dye molecule and gelatin." @default.
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- W1981799503 date "2005-01-01" @default.
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- W1981799503 title "Gelatin hydrogels cross-linked by γ-ray irradiation: materials for absorption and release of dye" @default.
- W1981799503 doi "https://doi.org/10.1163/1568562053992478" @default.
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