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• W1981837019 abstract "The motivation to understand the basic rules and principles governing molecular self-assembly may be relevant to explain in the context of molecular biology the self-organization and biological functions exhibited within cells. This paper presents a molecular automata model to simulate molecular self-assembly introducing the concept of molecular programming to simulate the biological function or operation performed by an assembled molecular state machine. The method is illustrated modelling Escherichia coli membrane construction including the assembly and operation of ATP synthase as well as the assembly of the bacterial flagellar motor. Flagellar motor operation was simulated using a different approach based on state machine definition used in virtual reality systems. The proposed methodology provides a modelling framework for simulation of biological functions performed by cellular components and other biological systems suitable to be modelled as molecular state machines." @default.
• W1981837019 created "2016-06-24" @default.
• W1981837019 creator A5012685225 @default.
• W1981837019 date "1997-12-01" @default.
• W1981837019 modified "2023-10-01" @default.
• W1981837019 title "Molecular automata assembly: principles and simulation of bacterial membrane construction" @default.
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• W1981837019 doi "https://doi.org/10.1016/s0303-2647(97)00048-8" @default.
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