FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981837666> ?p ?o ?g. }

• W1981837666 endingPage "42" @default.
• W1981837666 startingPage "34" @default.
• W1981837666 abstract "The conditioned place preference (CPP) paradigm entails Pavlovian conditioning and allows evaluating the acquisition and extinction of drug-associated memory. Epigenetic regulation of chromatin structure by acetylation and deacetylation of histone proteins is critical for formation of long-term memory (LTM). We have recently shown that a single administration of the histone deacetylase (HDAC) inhibitor sodium butyrate (NaB) facilitated extinction of fear-associated memory in mice. Using the CPP paradigm, the present study investigated the effect of NaB on cocaine-associated memory. C57B/6 mice were conditioned by either fixed daily doses of cocaine (5 mg/kg × 4 and 15 mg/kg × 4 days) or an escalating schedule (3, 6, 12 and 24 mg/kg). Acute administration of NaB (1.2 g/kg) prior to conditioning by fixed doses of cocaine increased the expression and impaired the extinction of place preference compared to control subjects. Subjects that were conditioned by 15 mg/kg × 4 cocaine and received a single injection of NaB following the first or the second CPP test showed impaired extinction compared to control mice that received saline instead of NaB. Subjects that were conditioned by escalating schedule of cocaine and subsequently received repeated injections of NaB during daily reexposure to nonreinforced context showed either enhancement or no effect on place preference. Acute administration of NaB (1.2 g/kg) to naïve mice resulted in marked increase in acetylation of histone H3 lysine 14 (H3K14) and histone H4 lysine 8 (H4K8) in hippocampus but not amygdala. Results suggest that regardless of the scheduling of either cocaine or NaB administration, NaB-induced histone hyperacetylation in the hippocampus may strengthen cocaine-associated contextual memory." @default.
• W1981837666 created "2016-06-24" @default.
• W1981837666 creator A5005844929 @default.
• W1981837666 creator A5024578974 @default.
• W1981837666 creator A5062737096 @default.
• W1981837666 date "2013-05-01" @default.
• W1981837666 modified "2023-10-16" @default.
• W1981837666 title "Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory" @default.
• W1981837666 cites W1576139686 @default.
• W1981837666 cites W1593787667 @default.
• W1981837666 cites W1969699111 @default.
• W1981837666 cites W1983267120 @default.
• W1981837666 cites W1983861034 @default.
• W1981837666 cites W1983963006 @default.
• W1981837666 cites W1989407684 @default.
• W1981837666 cites W1997789621 @default.
• W1981837666 cites W2001487449 @default.
• W1981837666 cites W2002928138 @default.
• W1981837666 cites W2005513120 @default.
• W1981837666 cites W2013152269 @default.
• W1981837666 cites W2014496001 @default.
• W1981837666 cites W2018652402 @default.
• W1981837666 cites W2032242574 @default.
• W1981837666 cites W2032680863 @default.
• W1981837666 cites W2037615960 @default.
• W1981837666 cites W2039674227 @default.
• W1981837666 cites W2042966900 @default.
• W1981837666 cites W2046355712 @default.
• W1981837666 cites W2065964622 @default.
• W1981837666 cites W2068735847 @default.
• W1981837666 cites W2068794037 @default.
• W1981837666 cites W2071761663 @default.
• W1981837666 cites W2074424302 @default.
• W1981837666 cites W2074489888 @default.
• W1981837666 cites W2084252221 @default.
• W1981837666 cites W2084856596 @default.
• W1981837666 cites W2090054406 @default.
• W1981837666 cites W2090760765 @default.
• W1981837666 cites W2096193724 @default.
• W1981837666 cites W2103425386 @default.
• W1981837666 cites W2106862702 @default.
• W1981837666 cites W2107980868 @default.
• W1981837666 cites W2115266490 @default.
• W1981837666 cites W2135950112 @default.
• W1981837666 cites W2137116499 @default.
• W1981837666 cites W2139384923 @default.
• W1981837666 cites W2141035945 @default.
• W1981837666 cites W2143658931 @default.
• W1981837666 cites W2146070554 @default.
• W1981837666 cites W2151062067 @default.
• W1981837666 cites W2153998371 @default.
• W1981837666 cites W2156243556 @default.
• W1981837666 cites W2160934587 @default.
• W1981837666 cites W2163773590 @default.
• W1981837666 cites W2169682903 @default.
• W1981837666 cites W4247458622 @default.
• W1981837666 cites W4323238075 @default.
• W1981837666 doi "https://doi.org/10.1016/j.nlm.2013.03.007" @default.
• W1981837666 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3654019" @default.
• W1981837666 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23567105" @default.
• W1981837666 hasPublicationYear "2013" @default.
• W1981837666 type Work @default.
• W1981837666 sameAs 1981837666 @default.
• W1981837666 citedByCount "50" @default.
• W1981837666 countsByYear W19818376662014 @default.
• W1981837666 countsByYear W19818376662015 @default.
• W1981837666 countsByYear W19818376662016 @default.
• W1981837666 countsByYear W19818376662017 @default.
• W1981837666 countsByYear W19818376662018 @default.
• W1981837666 countsByYear W19818376662019 @default.
• W1981837666 countsByYear W19818376662020 @default.
• W1981837666 countsByYear W19818376662021 @default.
• W1981837666 countsByYear W19818376662022 @default.
• W1981837666 countsByYear W19818376662023 @default.
• W1981837666 crossrefType "journal-article" @default.
• W1981837666 hasAuthorship W1981837666A5005844929 @default.
• W1981837666 hasAuthorship W1981837666A5024578974 @default.
• W1981837666 hasAuthorship W1981837666A5062737096 @default.
• W1981837666 hasBestOaLocation W19818376662 @default.
• W1981837666 hasConcept C100544194 @default.
• W1981837666 hasConcept C101991246 @default.
• W1981837666 hasConcept C104317684 @default.
• W1981837666 hasConcept C105795698 @default.
• W1981837666 hasConcept C119157956 @default.
• W1981837666 hasConcept C15744967 @default.
• W1981837666 hasConcept C169760540 @default.
• W1981837666 hasConcept C185592680 @default.
• W1981837666 hasConcept C199289684 @default.
• W1981837666 hasConcept C2776202225 @default.
• W1981837666 hasConcept C2776745794 @default.
• W1981837666 hasConcept C2776979534 @default.
• W1981837666 hasConcept C2778305200 @default.
• W1981837666 hasConcept C2778942008 @default.
• W1981837666 hasConcept C2779085176 @default.
• W1981837666 hasConcept C33923547 @default.
• W1981837666 hasConcept C35124327 @default.
• W1981837666 hasConcept C45262634 @default.
• W1981837666 hasConcept C48856860 @default.

• next